SCHEMBL5455602

SCHEMBL5455602

S=C(Nc1ccc(Br)cc1)Nc1ccc(Br)cc1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.83
ALDH1A1 P00352 5/20 0.83
MAOA P21397 2/20 0.83
MAOB P27338 2/20 0.83
MEN1 O00255 6/20 0.79
KMT2A Q03164 6/20 0.79
LMNA P02545 4/20 0.79
HTT P42858 3/20 0.79
CYP1A2 P05177 3/20 0.79
CYP2C19 P33261 3/20 0.79
SMN1; SMN2 Q16637 3/20 0.79
CYP3A4 P08684 2/20 0.79
MAPK1 P28482 1/20 0.79
IDO1 P14902 1/20 0.75
EPHX1 P07099 1/20 0.64
L3MBTL1 Q9Y468 2/20 0.63
CYP2D6 P10635 1/20 0.63
NPSR1 Q6W5P4 1/20 0.63
CYP2C9 P11712 1/20 0.62
GAA P10253 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8956372 1.00 MAPT (0.83) MAPTALDH1A1MAOAMAOBMEN1
SCHEMBL5137359 0.91 ALDH1A1 (1.00) MAPTALDH1A1MAOAMAOBMEN1
SCHEMBL8956193 0.89 CNR1 (0.70) MAPTALDH1A1MAOAMAOBMEN1
SCHEMBL11060530 0.89 CNR1 (0.70) MAPTALDH1A1MAOAMAOBMEN1
SCHEMBL7660223 0.89 MAPT (0.68) MAPTALDH1A1MAOAMAOBMEN1
SCHEMBL9036606 0.86 IDO1 (1.00) MAPTALDH1A1MAOAMAOBMEN1
SCHEMBL8956609 0.84 CYP1A2 (0.79) MAPTALDH1A1MAOAMAOBMEN1
Hydrochloric Acid SCHEMBL9004637 0.84 IDO1 (0.96) MAPTALDH1A1MAOAMAOBMEN1
SCHEMBL11067809 0.84 MEN1 (0.83) MAPTALDH1A1MAOAMAOBMEN1
SCHEMBL7660214 0.82 ALDH1A1 (0.67) MAPTALDH1A1MAOAMAOBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12427798-B2 Heat-sensitive recording composition NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2025-09-30 US disclosed
CN-119707777-A Synthesis method of asymmetric thiourea compound 浙江工业大学 2025-03-28 CN disclosed
US-20250001788-A1 HEAT-SENSITIVE RECORDING COMPOSITION NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2025-01-02 US disclosed
EP-4442468-A1 HEAT-SENSITIVE RECORDING COMPOSITION Nippon Kayaku Kabushiki Kaisha (JP) 2024-10-09 EP disclosed
EP-4442467-A1 THERMAL RECORDING COMPOSITION Nippon Kayaku Kabushiki Kaisha (JP) 2024-10-09 EP disclosed
US-20240326501-A1 HEAT-SENSITIVE RECORDING COMPOSITION NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2024-10-03 US disclosed
CN-112533967-B Oil-in-water droplet type emulsion of active energy ray-curable resin composition and thermosensitive recording material 日本化药株式会社 2023-09-15 CN disclosed
WO-2023100902-A1 HEAT-SENSITIVE RECORDING COMPOSITION 日本化薬株式会社 2023-06-08 WO disclosed
WO-2023100900-A1 THERMAL RECORDING COMPOSITION 日本化薬株式会社 2023-06-08 WO disclosed
WO-2017214505-A1 CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE BIOMARIN PHARMACEUTICAL INC. (US) 2017-12-14 WO disclosed
CN-101129295-B There is the binary initiator system of good storage stability and especially suitable for acidic system HERAEUS KULZER GMBH (DE) 2016-02-10 CN disclosed
US-20070040151-A1 Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems HERAEUS KULZER GMBH (DE) 2007-02-22 US disclosed
US-5234798-A Show previously hidden image on exposure to radiant energy DITTLER BROTHERS, INCORPORATED (US) 1993-08-10 US disclosed
US-4507670-A COLORING, IMAGES, LEUCO DYES RICOH COMPANY, LTD. (JP) 1985-03-26 US disclosed
US-4461821-A Photoconductive compositions and electrophotographic photosensitive materials comprising an organic photoconductor and a thiourea compound FUJI PHOTO FILM CO., LTD. (JP) 1984-07-24 US disclosed