Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CD4 | P01730 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16340138 | 0.78 | ABL1 (0.36) | L3MBTL1NOD1HTTALDH3A1POLB | |
| SCHEMBL26623444 | 0.76 | L3MBTL1 (0.53) | L3MBTL1NOD1HTTALDH3A1POLB | |
| SCHEMBL26623445 | 0.76 | MEN1 (0.37) | NOD1HTTALDH3A1POLBNOD2 | |
| SCHEMBL30743357 | 0.74 | HTT (0.44) | L3MBTL1NOD1HTTALDH3A1POLB | |
| SCHEMBL31590154 | 0.74 | SCN9A (0.35) | L3MBTL1HTTALDH3A1POLBMAPT | |
| SCHEMBL1777233 | 0.73 | PTGDR2 (0.42) | L3MBTL1NOD1HTTALDH3A1POLB | |
| SCHEMBL27041345 | 0.73 | L3MBTL1 (0.40) | L3MBTL1NOD1HTTALDH3A1POLB | |
| SCHEMBL5411150 | 0.73 | L3MBTL1 (0.38) | L3MBTL1NOD1HTTALDH3A1POLB | |
| SCHEMBL1749134 | 0.72 | L3MBTL1 (0.58) | L3MBTL1NOD1HTTALDH3A1POLB | |
| SCHEMBL1749156 | 0.69 | PTGDR2 (0.46) | L3MBTL1NOD1HTTALDH3A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215559-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | ARIA PHARMACEUTICALS, INC. (US) | 2023-11-09 | — | — | WO | disclosed |