Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30743526 | 0.78 | ALDH3A1 (0.53) | HTTL3MBTL1ALDH3A1NOD1POLB | |
| SCHEMBL1749156 | 0.78 | PTGDR2 (0.46) | HTTL3MBTL1ALDH3A1NOD1POLB | |
| SCHEMBL26623306 | 0.74 | L3MBTL1 (0.38) | HTTL3MBTL1ALDH3A1NOD1POLB | |
| SCHEMBL30743569 | 0.73 | L3MBTL1 (0.51) | HTTL3MBTL1ALDH3A1NOD1POLB | |
| SCHEMBL30743381 | 0.73 | SCN9A (0.38) | HTTALDH3A1ALDH1A1KDM4EMAPT | |
| SCHEMBL1777233 | 0.72 | PTGDR2 (0.42) | HTTL3MBTL1ALDH3A1NOD1POLB | |
| SCHEMBL1749021 | 0.71 | PTGDR2 (0.44) | HTTL3MBTL1ALDH3A1NOD1POLB | |
| SCHEMBL30668854 | 0.71 | PTGDR2 (0.44) | HTTL3MBTL1ALDH3A1NOD1POLB | |
| SCHEMBL1354451 | 0.71 | PTGDR2 (0.44) | HTTL3MBTL1ALDH3A1NOD1POLB | |
| SCHEMBL13014031 | 0.71 | PTGDR2 (0.44) | HTTL3MBTL1ALDH3A1NOD1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565584-A1 | 1H-PYRROLO[3,2-B]PYRIDINE DERIVATIVES AS IRREVERSIBLE INHIBITORS OF MUTANT EGFR FOR THE TREATMENT OF CANCER | Bayer Aktiengesellschaft (DE) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024028316-A1 | 1H-PYRROLO[3,2-B]PYRIDINE DERIVATIVES AS IRREVERSIBLE INHIBITORS OF MUTANT EGFR FOR THE TREATMENT OF CANCER | BAYER AKTIENGESELLSCHAFT (DE) | 2024-02-08 | — | — | WO | disclosed |