Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5413878 | 0.82 | NOD1 (0.39) | L3MBTL1PTGDR2ALDH3A1HTTNOD1 | |
| SCHEMBL14427711 | 0.82 | L3MBTL1 (0.39) | L3MBTL1PTGDR2ALDH3A1HTTNOD1 | |
| SCHEMBL1777233 | 0.81 | PTGDR2 (0.42) | L3MBTL1PTGDR2ALDH3A1HTTNOD1 | |
| SCHEMBL14427681 | 0.80 | ALDH3A1 (0.40) | L3MBTL1PTGDR2ALDH3A1HTTNOD1 | |
| SCHEMBL1749156 | 0.77 | PTGDR2 (0.46) | L3MBTL1PTGDR2ALDH3A1HTTNOD1 | |
| SCHEMBL5411086 | 0.76 | L3MBTL1 (0.50) | L3MBTL1ALDH3A1HTTNOD1POLB | |
| SCHEMBL16340138 | 0.75 | ABL1 (0.36) | L3MBTL1ALDH3A1HTTNOD1POLB | |
| SCHEMBL1749021 | 0.75 | PTGDR2 (0.44) | L3MBTL1PTGDR2ALDH3A1HTTNOD1 | |
| SCHEMBL1354451 | 0.75 | PTGDR2 (0.44) | L3MBTL1PTGDR2ALDH3A1HTTNOD1 | |
| SCHEMBL13014031 | 0.75 | PTGDR2 (0.44) | L3MBTL1PTGDR2ALDH3A1HTTNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7259154-B2 | Anticancer agents; asthma; rhintis; vision disorders; skin disorders; antiarthritic agents; antiinflammatory agents; antiallergens | AVENTIS PHARMACEUTICALS INC. (US) | 2007-08-21 | — | — | US | disclosed |
| US-20040142947-A1 | Pyrrolopyrimidines | AVENTIS PHARMACEUTICALS, INC. | 2004-07-22 | — | — | US | disclosed |
| EP-1404676-A1 | PYRROLOPYRIMIDINES AS PROTEIN KINASE INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003000695-A1 | PYRROLOPYRIMIDINES AS PROTEIN KINASE INHIBITORS | AVENTIS PHARMACEUTICALS INC (US) | 2003-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142947-A1 | Pyrrolopyrimidines | DPYD, TYMP, PNPO | L3MBTL1 3350/4885PTGDR2 772/4885ALDH3A1 309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.