SCHEMBL26624014

SCHEMBL26624014

COc1ccc(C(=O)CC(=O)c2ccc3c(c2)OCO3)cc1

nearest known ligand 0.72

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.72
MEN1 O00255 1/20 0.72
RAB9A P51151 6/20 0.67
NPC1 O15118 6/20 0.67
CTNNB1 P35222 4/20 0.66
WNT3A P56704 4/20 0.66
ALDH1A1 P00352 5/20 0.60
MAPT P10636 4/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
ALOX12 P18054 2/20 0.60
NFKB1 P19838 1/20 0.60
NFKB2 Q00653 1/20 0.60
RELA Q04206 1/20 0.60
LMNA P02545 1/20 0.57
GAA P10253 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15979976 0.91 CTNNB1 (0.78) KMT2AMEN1RAB9ANPC1CTNNB1
SCHEMBL14477069 0.87 RAB9A (0.62) KMT2AMEN1RAB9ANPC1CTNNB1
SCHEMBL2237626 0.86 MEN1 (0.76) KMT2AMEN1RAB9ANPC1CTNNB1
SCHEMBL29458253 0.86 MEN1 (0.76) KMT2AMEN1RAB9ANPC1CTNNB1
SCHEMBL4823544 0.84 RAB9A (0.68) KMT2AMEN1RAB9ANPC1CTNNB1
SCHEMBL13516462 0.84 MEN1 (1.00) KMT2AMEN1RAB9ANPC1CTNNB1
SCHEMBL25203201 0.83 RAB9A (0.70) KMT2AMEN1RAB9ANPC1CTNNB1
SCHEMBL652035 0.83 CTNNB1 (0.78) RAB9ANPC1CTNNB1WNT3AALDH1A1
SCHEMBL8961590 0.82 CTNNB1 (0.82) KMT2AMEN1RAB9ANPC1CTNNB1
SCHEMBL26717284 0.82 KMT2A (0.61) KMT2AMEN1RAB9ANPC1CTNNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023214706-A1 NOVEL DIARYL-PROPANEDIONE DERIVATIVE COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF INFLAMMATORY OR ALLERGIC DISEASES 엘림랜드 주식회사 2023-11-09 WO disclosed