SCHEMBL26624265

SCHEMBL26624265

CC[C@H]1O[C@@H](n2cnc3c(=O)[nH]c(N)nc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1COC(=O)NC

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ HINT1 P49773 7/20 0.52
▸ TAS1R3 Q7RTX0 1/20 0.48
▸ TAS1R1 Q7RTX1 1/20 0.48
▸ NT5E P21589 1/20 0.46
▸ GSK3A P49840 2/20 0.46
▸ RPS6KA3 P51812 2/20 0.46
▸ MAPK14 Q16539 2/20 0.46
▸ KRAS P01116 7/20 0.45
▸ TGM2 P21980 1/20 0.45
▸ PNP P00491 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26209876 0.93 HINT1 (0.49) HINT1TAS1R3TAS1R1NT5EGSK3A
SCHEMBL26624263 0.87 HINT1 (0.51) HINT1TAS1R3TAS1R1NT5EGSK3A
SCHEMBL26624645 0.86 HINT1 (0.51) HINT1TAS1R3TAS1R1NT5EGSK3A
SCHEMBL26624650 0.86 HINT1 (0.50) HINT1TAS1R3TAS1R1NT5EGSK3A
SCHEMBL26808492 0.83 HINT1 (0.51) HINT1TAS1R3TAS1R1NT5EGSK3A
SCHEMBL25807955 0.83 HINT1 (0.51) HINT1TAS1R3TAS1R1NT5EGSK3A
SCHEMBL16471919 0.83 HINT1 (0.51) HINT1TAS1R3TAS1R1NT5EGSK3A
SCHEMBL26624267 0.82 HINT1 (0.49) HINT1TAS1R3TAS1R1NT5EGSK3A
SCHEMBL26808279 0.81 HINT1 (0.49) HINT1TAS1R3TAS1R1NT5EGSK3A
SCHEMBL26209875 0.81 HINT1 (0.50) HINT1TAS1R3TAS1R1NT5EGSK3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF GUANGZHOU HENOVCOM BIOSCIENCE CO., LTD. (CN) 2023-10-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230340009-A1 COMPOUNDS FOR RNA CAPPING AND USES THEREOF RNGTT, RNMT, NSUN2 HINT1 706/4885TAS1R3 3664/4885TAS1R1 3824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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