Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.38 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.38 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20240947 | 1.00 | PLG (0.42) | PLGPLATLMNATPSAB1TPSD1 | |
| SCHEMBL1958023 | 0.87 | NAAA (0.31) | — | |
| Hydrazine SCHEMBL22505628 | 0.84 | GPR35 (0.33) | — | |
| SCHEMBL398217 | 0.84 | GPR35 (0.34) | — | |
| SCHEMBL13888375 | 0.80 | TPSAB1 (0.38) | PLGPLATLMNATPSAB1TPSD1 | |
| SCHEMBL17911018 | 0.79 | F2 (0.33) | F2 | |
| SCHEMBL4269678 | 0.79 | F2 (0.33) | F2 | |
| SCHEMBL19924308 | 0.78 | PLG (0.50) | PLGPLATLMNATPSAB1TPSD1 | |
| SCHEMBL6746634 | 0.77 | CYP19A1 (0.41) | — | |
| SCHEMBL9505982 | 0.76 | PLG (0.54) | PLGPLATLMNATPSAB1TPSD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699553-B1 | SUBSTITUTED DIAMINOCARBOXAMIDE AND DIAMINOCARBONITRILE PYRIMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARM LLC (US) | 2023-11-08 | — | — | EP | disclosed |