Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.50 |
| ▸ | MMP9 | P14780 | 4/20 | 0.50 |
| ▸ | MMP13 | P45452 | 4/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | GYS1 | P13807 | 7/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1765109 | 0.89 | MMP2 (0.60) | MMP2MMP9MMP13CAPN1MMP1 | |
| SCHEMBL30603052 | 0.83 | MMP2 (0.48) | MMP2MMP9MMP13CAPN1MMP1 | |
| SCHEMBL12555619 | 0.77 | MMP2 (0.46) | MMP2MMP9MMP13CAPN1MMP1 | |
| SCHEMBL1612206 | 0.76 | MMP2 (0.56) | MMP2MMP9MMP13CAPN1MMP1 | |
| SCHEMBL1611046 | 0.75 | MMP2 (0.64) | MMP2MMP9MMP13CAPN1MMP1 | |
| SCHEMBL1764763 | 0.74 | MMP2 (0.46) | MMP2MMP9MMP13CAPN1MMP1 | |
| SCHEMBL19401473 | 0.73 | GYS1 (0.45) | MMP2MMP9MMP13CAPN1MMP1 | |
| SCHEMBL1764679 | 0.73 | GYS1 (0.45) | MMP2MMP9MMP13CAPN1MMP1 | |
| SCHEMBL1764799 | 0.73 | KMT2A (0.38) | — | |
| SCHEMBL1765120 | 0.73 | KMT2A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023209090-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS AND THEIR APPLICATION IN THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2023-11-02 | — | — | WO | disclosed |