Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GYS1 | P13807 | 9/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1764679 | 1.00 | GYS1 (0.45) | GYS1MMP2MMP9MMP13MMP1 | |
| SCHEMBL19401544 | 0.86 | GYS1 (0.54) | GYS1MMP2MMP9MMP13FAAH | |
| SCHEMBL1764734 | 0.86 | GYS1 (0.54) | GYS1MMP2MMP9MMP13FAAH | |
| SCHEMBL1765109 | 0.82 | MMP2 (0.60) | GYS1MMP2MMP9MMP13MMP1 | |
| SCHEMBL1764763 | 0.81 | MMP2 (0.46) | GYS1MMP2MMP9MMP13MMP1 | |
| SCHEMBL12585485 | 0.78 | GYS1 (0.65) | GYS1MMP2MMP9MMP13MMP1 | |
| SCHEMBL12556131 | 0.76 | GYS1 (0.43) | GYS1FAAHHSD11B1BRD4SIRT2 | |
| SCHEMBL1764886 | 0.76 | HSD11B1 (0.42) | GYS1MMP2MMP9MMP13MMP1 | |
| SCHEMBL20676992 | 0.75 | MGLL (0.39) | — | |
| SCHEMBL30603052 | 0.72 | MMP2 (0.48) | GYS1MMP2MMP9MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11111240-B2 | Sultam compound and application method thereof | Chai Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2021-09-07 | — | — | US | disclosed |
| US-20210047314-A1 | Sultam Compound And Application Method Thereof | CENTAURUS BIOPHARMA CO., LTD. (CN) | 2021-02-18 | — | — | US | disclosed |
| EP-3434671-B1 | SULTAM COMPOUND AND APPLICATION METHOD THEREOF | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2020-10-21 | — | — | EP | disclosed |
| EP-3434671-A1 | SULTAM COMPOUND AND APPLICATION METHOD THEREOF | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-01-30 | — | — | EP | disclosed |
| WO-2017162157-A1 | SULTAM COMPOUND AND APPLICATION METHOD THEREOF | 正大天晴药业集团股份有限公司 | 2017-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11111240-B2 | Sultam compound and application method thereof | IDH1, IDH3A, IDH3B | GYS1 721/4885MMP2 1245/4885MMP9 627/4885 |
| US-20210047314-A1 | Sultam Compound And Application Method Thereof | IDH1, IDH3A, IDH3B | GYS1 721/4885MMP2 1245/4885MMP9 627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.