Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CES2 | O00748 | 5/20 | 0.53 |
| ▸ | CES1 | P23141 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Peroxide SCHEMBL29219018 | 1.00 | LMNA (0.56) | LMNACES2CES1ALDH1A1TSHR | |
| SCHEMBL28255372 | 0.98 | LMNA (0.55) | LMNACES2CES1ALDH1A1TSHR | |
| SCHEMBL7678289 | 0.94 | ALDH1A1 (0.56) | LMNACES2CES1ALDH1A1TSHR | |
| SCHEMBL7678291 | 0.94 | ALDH1A1 (0.56) | LMNACES2CES1ALDH1A1TSHR | |
| SCHEMBL20485512 | 0.90 | ALDH1A1 (0.58) | LMNACES2CES1ALDH1A1TSHR | |
| SCHEMBL1535709 | 0.89 | CES2 (0.56) | LMNACES2CES1ALDH1A1TSHR | |
| SCHEMBL9318015 | 0.88 | LMNA (0.56) | LMNACES2CES1ALDH1A1TSHR | |
| SCHEMBL7153333 | 0.87 | CES2 (0.57) | LMNACES2CES1TSHRL3MBTL1 | |
| SCHEMBL2149478 | 0.86 | CES2 (0.58) | LMNACES2CES1ALDH1A1TSHR | |
| SCHEMBL7156909 | 0.86 | CES2 (0.58) | LMNACES2CES1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 653 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920107-B | Synthetic method of lobeline hydrochloride | 上海万巷制药有限公司 | 2022-09-13 | — | — | CN | claimed |
| CN-113200855-B | Preparation method of ethyl benzoylacetate | 江苏巨莱生物医药有限公司 | 2022-06-03 | — | — | CN | claimed |
| CN-110483290-B | Method for synthesizing beta-keto ester by copper catalysis | 上海应用技术大学 | 2022-05-31 | — | — | CN | claimed |
| EP-3947712-A1 | INTESTINAL BIOMARKERS FOR GUT HEALTH IN DOMESTICATED BIRDS | DuPont Nutrition Biosciences ApS (DK) | 2022-02-09 | — | — | EP | claimed |
| EP-3947713-A1 | INTESTINAL BIOMARKERS FOR GUT HEALTH IN DOMESTICATED BIRDS | DuPont Nutrition Biosciences ApS (DK) | 2022-02-09 | — | — | EP | claimed |
| CN-113200855-A | Preparation method of ethyl benzoylacetate | 江苏巨莱生物医药有限公司 | 2021-08-03 | — | — | CN | claimed |
| CN-112920107-A | Synthetic method of lobeline hydrochloride | 上海万巷制药有限公司 | 2021-06-08 | — | — | CN | claimed |
| CN-112209907-A | Method for synthesizing dihydrofuran containing 1, 3-indene dione spiro-skeleton by using microchannel reaction device | 南京先进生物材料与过程装备研究院有限公司 | 2021-01-12 | — | — | CN | claimed |
| CN-111875494-A | Benzoyl butyrate derivative and preparation method thereof | 无锡极电光能科技有限公司 | 2020-11-03 | — | — | CN | claimed |
| CN-109233323-B | Preparation method of disperse blue 354 | 浙江闰土研究院有限公司 | 2020-10-09 | — | — | CN | claimed |
| US-5561157-A | INCLUDES ORGANIC ALPHA AND BETA HYDROXY OR KETO CARBOXYLIC ACIDS, ESTERS, LACTONES AND/OR SALTS; USED FOR SKIN DISORDERS | TRISTRATA INC (US) | 1996-10-01 | — | — | US | claimed |
| US-5561158-A | Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging | TRISTRATA, INCORPORATED | 1996-10-01 | — | — | US | claimed |
| US-5554654-A | COMPRISING SALICYLIC ACID, RETINOIC ACID, ERYTHROMYCIN, METRONIDAZOLE, TETRACYCLINE, CLINDAMYCIN, MINOCYCLINE, MECLOCYCLINE OR BENZILIC ACID BY COMBINING WITH 2-HYDROXY ACID, 2-KETOACID, DERIVATIVE THEREOF OR RELATED COMPOUND | TRISTRATA INC (US) | 1996-09-10 | — | — | US | claimed |
| US-5554597-A | Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging | TRISTRATA INC (US) | 1996-09-10 | — | — | US | claimed |
| US-5554652-A | TOPICALLY APPLYING MIXTURE TO REDUCE OR PREVENT SKIN DISORDERS | TRISTRATA INC (US) | 1996-09-10 | — | — | US | claimed |
| EP-0273202-B1 | Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. | SCOTT EUGENE J VAN (US) | 1995-06-21 | — | — | EP | claimed |
| CN-1090133-A | The polyol polyester that contains the difference esterification can not digestion type fat combination with the control passive oil loss | PROCTER & GAMBLE (US) | 1994-08-03 | — | — | CN | claimed |
| EP-0599819-A2 | Additives enhancing topical actions of therapeutic agents | Van Scott, Eugene J., Dr. (US) | 1994-06-01 | — | — | EP | claimed |
| EP-0045976-B1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Montedison S.p.A. (IT) | 1989-11-23 | — | — | EP | claimed |
| EP-0273202-A2 | Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. | Van Scott, Eugene J., Dr. (US) | 1988-07-06 | — | — | EP | claimed |