Sugi Predict

Sugi Predict / Compounds / SCHEMBL26628124

SCHEMBL26628124

SCHEMBL26628124

CC#CCC(C)[C@H](O)/C=C/[C@@H]1[C@H]2CC(=CCCCC(=O)OC)C[C@H]2C[C@H]1O

nearest known ligand 0.82

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ PTGIR P43119 2/20 0.82
▸ PTGER1 P34995 1/20 0.82
▸ PTGER3 P43115 1/20 0.82
▸ PTGER2 P43116 1/20 0.82
▸ PTGDR Q13258 1/20 0.82
▸ PPARD Q03181 2/20 0.52
▸ PPARA Q07869 2/20 0.52
▸ PPARG P37231 1/20 0.52
▸ MEN1 O00255 1/20 0.52
▸ KMT2A Q03164 1/20 0.52
▸ TBXA2R P21731 10/20 0.38
▸ ALDH1A1 P00352 2/20 0.37
▸ KDM4E B2RXH2 1/20 0.37
▸ HKDC1 Q2TB90 1/20 0.37
▸ TDP1 Q9NUW8 1/20 0.37
▸ SAE1 Q9UBE0 1/20 0.37
▸ UBA2 Q9UBT2 1/20 0.37
▸ PTGER4 P35408 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10345585 1.00 PTGIR (0.82) PTGIRPTGER1PTGER3PTGER2PTGDR
SCHEMBL26628155 1.00 PTGIR (0.82) PTGIRPTGER1PTGER3PTGER2PTGDR
SCHEMBL26628115 1.00 PTGIR (0.82) PTGIRPTGER1PTGER3PTGER2PTGDR
SCHEMBL26628139 1.00 PTGIR (0.82) PTGIRPTGER1PTGER3PTGER2PTGDR
SCHEMBL21509204 1.00 PTGIR (0.82) PTGIRPTGER1PTGER3PTGER2PTGDR
SCHEMBL21509173 1.00 PTGIR (0.82) PTGIRPTGER1PTGER3PTGER2PTGDR
SCHEMBL21509152 1.00 PTGIR (0.82) PTGIRPTGER1PTGER3PTGER2PTGDR
SCHEMBL21509146 1.00 PTGIR (0.82) PTGIRPTGER1PTGER3PTGER2PTGDR
SCHEMBL21973569 1.00 PTGIR (0.82) PTGIRPTGER1PTGER3PTGER2PTGDR
SCHEMBL10636092 0.92 PTGIR (0.80) PTGIRPTGER1PTGER3PTGER2PTGDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304519-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES CHIROGATE INTERNATIONAL INC. (TW) 2025-10-02 — — US disclosed
US-12428361-B2 Processes and intermediates for the preparation of carbaprostacyclin analogues CHIROGATE INTERNATIONAL INC. (TW) 2025-09-30 — — US disclosed
US-12221411-B2 Processes and intermediates for the preparation of carbaprostacyclin analogues CHIROGATE INTERNATIONAL INC. (TW) 2025-02-11 — — US disclosed
US-20240025832-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES CHIROGATE INTERNATIONAL INC. (TW) 2024-01-25 — — US disclosed
US-20230357118-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES CHIROGATE INTERNATIONAL INC. (TW) 2023-11-09 — — US disclosed
US-20230357119-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES CHIROGATE INTERNATIONAL INC. (TW) 2023-11-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12428361-B2 Processes and intermediates for the preparation of carbaprostacyclin analogues PTGIS, PTGIR, PTGES PTGIR 2/4885PTGER1 5/4885PTGER3 16/4885
US-20230357119-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES PTGIS, PTGIR, PTGES PTGIR 2/4885PTGER1 5/4885PTGER3 16/4885
US-20230357118-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES PTGIS, PTGIR, PTGES PTGIR 2/4885PTGER1 5/4885PTGER3 16/4885
US-12221411-B2 Processes and intermediates for the preparation of carbaprostacyclin analogues PTGIS, PTGIR, PTGES PTGIR 2/4885PTGER1 5/4885PTGER3 16/4885
US-20240025832-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES PTGIS, PTGIR, PTGES PTGIR 2/4885PTGER1 5/4885PTGER3 16/4885
US-20250304519-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES PTGIS, PTGIR, PTGES PTGIR 2/4885PTGER1 5/4885PTGER3 16/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.