Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.82 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.82 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.82 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.82 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.82 |
| ▸ | PPARD | Q03181 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 10/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345585 | 1.00 | PTGIR (0.82) | PTGIRPTGER1PTGER3PTGER2PTGDR | |
| SCHEMBL26628115 | 1.00 | PTGIR (0.82) | PTGIRPTGER1PTGER3PTGER2PTGDR | |
| SCHEMBL26628139 | 1.00 | PTGIR (0.82) | PTGIRPTGER1PTGER3PTGER2PTGDR | |
| SCHEMBL26628124 | 1.00 | PTGIR (0.82) | PTGIRPTGER1PTGER3PTGER2PTGDR | |
| SCHEMBL21509204 | 1.00 | PTGIR (0.82) | PTGIRPTGER1PTGER3PTGER2PTGDR | |
| SCHEMBL21509173 | 1.00 | PTGIR (0.82) | PTGIRPTGER1PTGER3PTGER2PTGDR | |
| SCHEMBL21509152 | 1.00 | PTGIR (0.82) | PTGIRPTGER1PTGER3PTGER2PTGDR | |
| SCHEMBL21509146 | 1.00 | PTGIR (0.82) | PTGIRPTGER1PTGER3PTGER2PTGDR | |
| SCHEMBL21973569 | 1.00 | PTGIR (0.82) | PTGIRPTGER1PTGER3PTGER2PTGDR | |
| SCHEMBL10636092 | 0.92 | PTGIR (0.80) | PTGIRPTGER1PTGER3PTGER2PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304519-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES | CHIROGATE INTERNATIONAL INC. (TW) | 2025-10-02 | — | — | US | disclosed |
| US-12428361-B2 | Processes and intermediates for the preparation of carbaprostacyclin analogues | CHIROGATE INTERNATIONAL INC. (TW) | 2025-09-30 | — | — | US | disclosed |
| US-12221411-B2 | Processes and intermediates for the preparation of carbaprostacyclin analogues | CHIROGATE INTERNATIONAL INC. (TW) | 2025-02-11 | — | — | US | disclosed |
| US-20240025832-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES | CHIROGATE INTERNATIONAL INC. (TW) | 2024-01-25 | — | — | US | disclosed |
| US-20230357119-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES | CHIROGATE INTERNATIONAL INC. (TW) | 2023-11-09 | — | — | US | disclosed |
| US-20230357118-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES | CHIROGATE INTERNATIONAL INC. (TW) | 2023-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12428361-B2 | Processes and intermediates for the preparation of carbaprostacyclin analogues | PTGIS, PTGIR, PTGES | PTGIR 2/4885PTGER1 5/4885PTGER3 16/4885 |
| US-20230357119-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES | PTGIS, PTGIR, PTGES | PTGIR 2/4885PTGER1 5/4885PTGER3 16/4885 |
| US-20230357118-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES | PTGIS, PTGIR, PTGES | PTGIR 2/4885PTGER1 5/4885PTGER3 16/4885 |
| US-12221411-B2 | Processes and intermediates for the preparation of carbaprostacyclin analogues | PTGIS, PTGIR, PTGES | PTGIR 2/4885PTGER1 5/4885PTGER3 16/4885 |
| US-20240025832-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES | PTGIS, PTGIR, PTGES | PTGIR 2/4885PTGER1 5/4885PTGER3 16/4885 |
| US-20250304519-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES | PTGIS, PTGIR, PTGES | PTGIR 2/4885PTGER1 5/4885PTGER3 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.