Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15842662 | 0.81 | HSD17B3 (0.69) | HSD17B3MEN1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL22501677 | 0.80 | CA9 (0.69) | CA1CA2CA5ACA9HSD17B3 | |
| SCHEMBL15842777 | 0.78 | HSD17B3 (0.55) | CA1CA2CA5ACA9HSD17B3 | |
| SCHEMBL26628214 | 0.76 | AR (0.53) | ALDH1A1HSD17B10KDM4EHPGDAR | |
| SCHEMBL10790823 | 0.74 | ALDH1A1 (0.68) | CA9HSD17B3ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL31623112 | 0.74 | ALDH1A1 (0.68) | CA9HSD17B3ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL29097458 | 0.74 | NPC1 (0.50) | CA1CA9HSD17B3MEN1ALDH1A1 | |
| SCHEMBL15842571 | 0.72 | PGR (0.58) | CA1CA2CA5ACA9MEN1 | |
| SCHEMBL15842562 | 0.71 | PIM1 (0.47) | CA1CA2CA5ACA9HSD17B3 | |
| SCHEMBL15842829 | 0.71 | MCL1 (0.58) | HSD17B3MEN1ALDH1A1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12129260-B2 | Benzofuro[3,2-c]chromen-6-one compounds as antibacterial agents | King Faisal University (SA) | 2024-10-29 | — | — | US | disclosed |
| US-20240279235-A1 | BENZOFURO[3,2-C]CHROMEN-6-ONE COMPOUNDS AS ANTIBACTERIAL AGENTS | King Faisal University (SA) | 2024-08-22 | — | — | US | disclosed |
| US-11976080-B1 | Benzofuro[3,2-c]chromen-6-one compounds as antibacterial agents | King Faisal University (SA) | 2024-05-07 | — | — | US | disclosed |
| US-11802130-B1 | Benzofuro[3,2-c]chromen-6-one compounds as antibacterial agents | King Faisal University (SA) | 2023-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279235-A1 | BENZOFURO[3,2-C]CHROMEN-6-ONE COMPOUNDS AS ANTIBACTERIAL AGENTS | TOP2A, TOP2B, TOP1 | CA1 4789/4885CA2 2557/4885CA5A 2594/4885 |
| US-11802130-B1 | Benzofuro[3,2-c]chromen-6-one compounds as antibacterial agents | TOP2A, TOP2B, TOP1 | CA1 4789/4885CA2 2557/4885CA5A 2594/4885 |
| US-11976080-B1 | Benzofuro[3,2-c]chromen-6-one compounds as antibacterial agents | TOP2A, TOP2B, TOP1 | CA1 4789/4885CA2 2557/4885CA5A 2594/4885 |
| US-12129260-B2 | Benzofuro[3,2-c]chromen-6-one compounds as antibacterial agents | TOP2A, TOP2B, TOP1 | CA1 4789/4885CA2 2557/4885CA5A 2594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.