Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | PGR | P06401 | 2/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14638474 | 0.77 | NPC1 (0.68) | ALDH1A1HPGDLMNACYP1A2PGR | |
| SCHEMBL14554206 | 0.77 | RAB9A (0.66) | ALDH1A1LMNANPC1RAB9AKMT2A | |
| Oxybenzone SCHEMBL11414020 | 0.76 | HPGD (0.97) | ALDH1A1HPGDLMNACYP1A2PGR | |
| SCHEMBL6763008 | 0.75 | CXCR2 (0.67) | ALDH1A1HPGDHTTNPC1RAB9A | |
| SCHEMBL12641906 | 0.75 | NPC1 (0.78) | MAPK1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL2743116 | 0.75 | NPC1 (0.78) | MAPK1NPC1RAB9AKMT2AMEN1 | |
| 4-Methoxysalicylic Acid SCHEMBL483346 | 0.74 | NPC1 (0.75) | ALDH1A1HPGDLMNACYP1A2PGR | |
| Oxybenzone SCHEMBL5161586 | 0.74 | HPGD (1.00) | ALDH1A1HPGDLMNACYP1A2PGR | |
| Oxybenzone SCHEMBL15551 | 0.74 | HPGD (1.00) | ALDH1A1HPGDLMNACYP1A2PGR | |
| Oxybenzone SCHEMBL29355332 | 0.74 | HPGD (1.00) | ALDH1A1HPGDLMNACYP1A2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230338340-A1 | Methods of Treating Cystic Fibrosis | DARTMOUTH COLLEGE (US) | 2023-10-26 | — | — | US | claimed |
| WO-2022094079-A1 | METHODS OF TREATING CYSTIC FIBROSIS | THE TRUSTEES OF DARTMOUTH COLLEGE (US) | 2022-05-05 | — | — | WO | claimed |
| US-20230338340-A1 | Methods of Treating Cystic Fibrosis | DARTMOUTH COLLEGE (US) | 2023-10-26 | — | — | US | disclosed |
| US-20230338340-A1 | Methods of Treating Cystic Fibrosis | DARTMOUTH COLLEGE (US) | 2023-10-26 | — | — | US | disclosed |
| WO-2022094079-A1 | METHODS OF TREATING CYSTIC FIBROSIS | THE TRUSTEES OF DARTMOUTH COLLEGE (US) | 2022-05-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230338340-A1 | Methods of Treating Cystic Fibrosis | CFTR, DAB2IP, CTTN | ALDH1A1 3332/4885HPGD 2613/4885LMNA 3412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.