DAB2IP

Disabled homolog 2-interacting protein · Q5VWQ8 · DAB2IP on Sugi Atlas →

1,011 patent compounds predicted against DAB2IP, 943 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
Apomorphine Apomorphine (SCHEMBL8524) 1.00 1/20
SCHEMBL225052 SCHEMBL225052 1.00 1/20
SCHEMBL225053 SCHEMBL225053 1.00 1/20
Apomorphine Apomorphine (SCHEMBL5904190) 1.00 1/20
SCHEMBL6010005 SCHEMBL6010005 1.00 1/20
Apomorphine Apomorphine (SCHEMBL232473) 0.98 1/20
Apomorphine Apomorphine (SCHEMBL1321033) 0.98 1/20
Apomorphine Apomorphine (SCHEMBL4755216) 0.98 1/20
Apomorphine Apomorphine (SCHEMBL5429071) 0.98 1/20
Apomorphine Apomorphine (SCHEMBL2256775) 0.89 1/20
SCHEMBL2617357 SCHEMBL2617357 0.84 1/20
SCHEMBL3868013 SCHEMBL3868013 0.84 1/20
SCHEMBL4206793 SCHEMBL4206793 0.84 1/20
SCHEMBL4206797 SCHEMBL4206797 0.84 1/20
SCHEMBL5025553 SCHEMBL5025553 0.84 1/20
SCHEMBL960282 SCHEMBL960282 0.82 1/20
SCHEMBL3972093 SCHEMBL3972093 0.82 1/20
SCHEMBL3972095 SCHEMBL3972095 0.82 1/20
SCHEMBL4061425 SCHEMBL4061425 0.82 1/20
SCHEMBL4749406 SCHEMBL4749406 0.82 1/20

Clinical trials — most relevant to DAB2IP by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Study Evaluating Toxicity & Efficacy of Lenalidomide(Revlimid®)in Chemotherapy-Naïve AIPC Patients PHASE2COMPLETED
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Genetic Markers and Biomarkers in Patients With Intellectual Disabilities of Genetic Origin nanRECRUITING
Child Development and Genetic Biomarkers(II): Gene Verification and Data Integration nanUNKNOWN
Molecular Diagnosis of Syndromic or Isolated Severe Intellectual Disability Using Whole Exome Sequencing : a Pilot Study nanCOMPLETED
Research and Characterization of New Genes Involved in Intellectual Disability nanCOMPLETED
Evaluation of CEMIP in Pancreatic Cancer nanUNKNOWN
Investigating Phenotypic, Epigenetic, and NeuroGenetic Traits in Rare and Ultra-rare Neurodevelopmental Disorders (Project PENGUIN) nanRECRUITING
Immune Cell Response to Stimuli nanRECRUITING
Search for Phenotype-modifying Genes in Patients With Intellectual Disabilities. nanNOT_YET_RECRUITING
Study of the Genetic Factors Involved in Autism and Related Disorders nanRECRUITING
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Muscle Tissue Bank for Muscular Dystrophy nanCOMPLETED
Gait in Rare Diseases nanCOMPLETED
Consortium On Risk for Early-onset Parkinson's Disease (CORE PD) nanCOMPLETED
Biological Signatures Resulting From Occupational Exposure to Complex Mixtures of PAHs nanUNKNOWN
Identification of New Genes Implicated in Rare Neurosensory Diseases by Whole Exome Sequencing nanUNKNOWN
Changes in Skin Innervation of Neurologically Asymptomatic Type 2 Diabetic Patients: the Correlation With the Diabetic Parameters and Neurotrophins. nanUNKNOWN
Exome Evaluation in Patients Living With Diabetes Complicated by Charcot Neuroarthropathy. nanCOMPLETED
Action Medical Research nanCOMPLETED
Evaluation of Brain Dysfunction in Patients with Duchene Muscular Dystrophy nanNOT_YET_RECRUITING
Group CBT in Adolescents With Fragile X Syndrome and in Adolescents With Autism Spectrum Disorder nanRECRUITING
Genetic Analysis of Hereditary Disorders of Hearing and Balance nanCOMPLETED
Biomarker Research in Inherited Movement Disorders nanRECRUITING
Lymphoid Tyrosine Phosphatase Gene Polymorphisms in Inflammatory Bowel Disease nanUNKNOWN
Velocardiofacial (VCFS; 22q11.2; DiGeorge) Syndrome Study nanCOMPLETED
CNKSR2 Natural History Study nanRECRUITING
Speech and Short-term Memory Functions in Dyslexia: a Combined MEG and EEG Study nanUNKNOWN
Exome Analysis in Hearing Impaired Patients nanUNKNOWN
Genetics and Psychopathology in the 22q11 Deletion Syndrome nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a DAB2IP binder may also engage these)

ProteinNameSimilarity
Q3UHC7 1.000 Q3UHC7 →
F6SEU4 1.000 F6SEU4 →
Q6P730 1.000 Q6P730 →
Q9QUH6 0.997 Q9QUH6 →
Q96PV0 0.997 Q96PV0 →
Q9UJF2 0.995 Q9UJF2 →
Q5PRF9 0.994 Q5PRF9 →
Q9H329 0.993 Q9H329 →
Q9BQI7 0.993 Q9BQI7 →
Q8R0S2 0.993 Q8R0S2 →
Q6DN90 0.992 Q6DN90 →
MAP3K9 Mitogen-activated protein kinase kinase kinase 9 0.992 landscape →
O15013 0.992 O15013 →
Q80XS6 0.992 Q80XS6 →
Q8TDY4 0.992 Q8TDY4 →
Q9ES67 0.992 Q9ES67 →
O60292 0.991 O60292 →
Q6P1I6 0.991 Q6P1I6 →
Q2TAL5 0.991 Q2TAL5 →
Q1LYM3 0.991 Q1LYM3 →
Q8MLZ5 0.991 Q8MLZ5 →
O43182 0.991 O43182 →
Q9VLW2 0.991 Q9VLW2 →
Q6ZSZ5 0.990 Q6ZSZ5 →
O14827 0.990 O14827 →
A9C3W3 0.990 A9C3W3 →
E1BFE9 0.990 E1BFE9 →
Q6UXY1 0.990 Q6UXY1 →
Q8JZP9 0.990 Q8JZP9 →
A1Z7A6 0.989 A1Z7A6 →