Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 1.00 |
| ▸ | HRH1 | P35367 | 7/20 | 1.00 |
| ▸ | DRD3 | P35462 | 7/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 7/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 6/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 6/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 5/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 5/20 | 1.00 |
| ▸ | HTR2A | P28223 | 5/20 | 1.00 |
| ▸ | HTR2B | P41595 | 5/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 5/20 | 1.00 |
| ▸ | HTR2C | P28335 | 4/20 | 1.00 |
| ▸ | DRD1 | P21728 | 4/20 | 1.00 |
| ▸ | CHRM5 | P08912 | 2/20 | 1.00 |
| ▸ | ADRA1D | P25100 | 2/20 | 1.00 |
| ▸ | HTR6 | P50406 | 2/20 | 1.00 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.69 |
| ▸ | LMNA | P02545 | 5/20 | 0.69 |
| ▸ | HTR1A | P08908 | 5/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pipamazine SCHEMBL49665 | 1.00 | DRD2 (1.00) | DRD2HRH1DRD3CYP2D6SLC6A2 | |
| Pipamazine SCHEMBL30627529 | 1.00 | DRD2 (1.00) | DRD2HRH1DRD3CYP2D6SLC6A2 | |
| Pipamazine SCHEMBL30307637 | 1.00 | DRD2 (1.00) | DRD2HRH1DRD3CYP2D6SLC6A2 | |
| SCHEMBL14437190 | 0.85 | CYP2D6 (0.74) | DRD2HRH1DRD3CYP2D6SLC6A2 | |
| SCHEMBL23898817 | 0.85 | DRD2 (0.74) | DRD2HRH1DRD3CYP2D6SLC6A2 | |
| SCHEMBL11743885 | 0.85 | DRD2 (0.73) | DRD2HRH1DRD3CYP2D6SLC6A2 | |
| Metopimazine SCHEMBL29462317 | 0.84 | DRD3 (1.00) | DRD2HRH1DRD3CYP2D6SLC6A2 | |
| Metopimazine SCHEMBL30038347 | 0.84 | DRD3 (1.00) | DRD2HRH1DRD3CYP2D6SLC6A2 | |
| SCHEMBL23921987 | 0.84 | HRH1 (0.73) | DRD2HRH1DRD3CYP2D6SLC6A2 | |
| Metopimazine SCHEMBL49905 | 0.84 | DRD3 (1.00) | DRD2HRH1DRD3CYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230346820-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF SARS-COV-2 | THE SCRIPPS RESEARCH INSTITUTE | 2023-11-02 | — | — | US | claimed |
| US-20250276066-A1 | METHODS, COMPOSITIONS AND COMPOUNDS FOR TREATING AGE-RELATED DISEASES AND CONDITIONS | GERO PTE LTD (SG) | 2025-09-04 | — | — | US | disclosed |
| EP-4291239-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING AGE-RELATED DISEASES AND CONDITIONS | GERO PTE. LTD. (SG) | 2023-12-20 | — | — | EP | disclosed |
| WO-2022173333-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING AGE-RELATED DISEASES AND CONDITIONS | GERO PTE. LTD. (SG) | 2022-08-18 | — | — | WO | disclosed |
| CN-100398519-C | Tetracyclic benzamide derivatives and methods of use thereof | INOTEK PHARMACEUTICALS CORP (US) | 2008-07-02 | — | — | CN | disclosed |
| CN-1780624-A | Tetracyclic benzamide derivatives and methods of use thereof | INOTEK PHARMACEUTICALS CORP (US) | 2006-05-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230346820-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF SARS-COV-2 | ACE2, SARS1, ACE | DRD2 3952/4885HRH1 1365/4885DRD3 4061/4885 |
| US-20250276066-A1 | METHODS, COMPOSITIONS AND COMPOUNDS FOR TREATING AGE-RELATED DISEASES AND CONDITIONS | UPF1, NLN, BRCA1 | DRD2 4318/4885HRH1 3405/4885DRD3 4400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.