Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 3/20 | 0.57 |
| ▸ | GLP1R | P43220 | 1/20 | 0.57 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.47 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NME4 | O00746 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | GCDH | Q92947 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2663152 | 0.84 | GCGR (0.58) | GCGRGLP1REPHX2TPSAB1 | |
| SCHEMBL4095979 | 0.83 | HDAC1 (0.53) | GCGRGLP1RMEN1KMT2ATDP1 | |
| SCHEMBL2662956 | 0.78 | GCGR (0.61) | GCGRGLP1REPHX2 | |
| SCHEMBL2663009 | 0.77 | GCGR (0.79) | GCGRGLP1REPHX2TPSAB1GAA | |
| SCHEMBL3187483 | 0.72 | SIRT5 (0.58) | ERCC1ERCC4GAANME4ADORA3 | |
| SCHEMBL4096606 | 0.72 | GCGR (0.45) | GCGRGLP1REPHX2 | |
| SCHEMBL2663137 | 0.72 | ACHE (0.54) | MEN1KMT2ACA1CA2CA9 | |
| SCHEMBL2663201 | 0.72 | GCGR (0.53) | GCGRGLP1REPHX2KMT2AGCG | |
| SCHEMBL4092836 | 0.71 | GCGR (0.62) | GCGRGLP1R | |
| SCHEMBL2663011 | 0.71 | CXCR3 (0.53) | GCGRGLP1RKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |