Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 12/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | TACR2 | P21452 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SHBG | P04278 | 1/20 | 0.49 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15315141 | 0.97 | SMN1; SMN2 (0.48) | SPHK1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL27401807 | 0.95 | THRB (0.47) | SPHK1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL27321008 | 0.90 | L3MBTL1 (0.47) | SPHK1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL11473790 | 0.89 | ALDH1A1 (0.56) | SPHK1KDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL1417508 | 0.89 | ALDH1A1 (0.56) | SPHK1KDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL11513573 | 0.89 | ALDH1A1 (0.56) | SPHK1KDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL39138 | 0.89 | ALDH1A1 (0.56) | SPHK1KDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL11520102 | 0.89 | ALDH1A1 (0.56) | SPHK1KDM4EALDH1A1TP53CYP3A4 | |
| SCHEMBL11245025 | 0.89 | SPHK1 (0.49) | SPHK1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL26814469 | 0.88 | L3MBTL1 (0.47) | SPHK1KDM4EALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215696-A1 | MODIFIED PYRIDINE-2,6-BIS(PHENYLENEPHENOLATE) COMPLEXES WITH ENHANCED SOLUBILITY THAT ARE USEFUL AS CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2023-11-09 | — | — | WO | disclosed |
| WO-2023215693-A1 | SUBSTITUTED PYRIDINE-2,6-BIS(PHENYLENEPHENOLATE) COMPLEXES WITH ENHANCED SOLUBILITY THAT ARE USEFUL AS CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2023-11-09 | — | — | WO | disclosed |