Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487736 | 0.81 | HDAC4 (0.54) | EGFRPDGFRBKDRKDM4EALDH1A1 | |
| SCHEMBL11736622 | 0.75 | ALDH1A1 (0.43) | EGFRPDGFRBKDRKDM4EALDH1A1 | |
| SCHEMBL259779 | 0.73 | AKR1B1 (0.59) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13038659 | 0.73 | AKR1B1 (0.59) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL18540795 | 0.73 | PDGFRB (0.51) | EGFRPDGFRBKDRKDM4EALDH1A1 | |
| SCHEMBL13800097 | 0.71 | KDM4E (0.40) | EGFRPDGFRBKDRKDM4EALDH1A1 | |
| SCHEMBL17528551 | 0.71 | PDGFRB (0.56) | EGFRPDGFRBKDRKDM4EALDH1A1 | |
| SCHEMBL8393507 | 0.69 | NQO1 (0.67) | PDGFRBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29919905 | 0.69 | NQO1 (0.67) | PDGFRBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL15772680 | 0.69 | NQO1 (0.47) | KDRKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |