Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 18/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26633912 | 0.82 | NAMPT (0.44) | NAMPTKEAP1NFE2L2 | |
| SCHEMBL26633796 | 0.80 | SMN1; SMN2 (0.44) | KEAP1NFE2L2 | |
| SCHEMBL26633900 | 0.80 | NAMPT (0.46) | NAMPT | |
| SCHEMBL26633778 | 0.76 | MEN1 (0.49) | KEAP1NFE2L2 | |
| SCHEMBL24011313 | 0.73 | NAMPT (0.44) | NAMPTKEAP1NFE2L2 | |
| SCHEMBL26784439 | 0.73 | NAMPT (0.42) | NAMPT | |
| SCHEMBL24011628 | 0.70 | NAMPT (0.43) | NAMPT | |
| SCHEMBL20233602 | 0.65 | NAMPT (0.48) | NAMPT | |
| SCHEMBL24011265 | 0.63 | KEAP1 (0.50) | NAMPTKEAP1NFE2L2 | |
| SCHEMBL15534874 | 0.63 | NAMPT (0.45) | NAMPTKEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | NAMPT, NNT, NAPRT | NAMPT 1/4885KEAP1 2111/4885NFE2L2 1578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.