Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 16/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25593244 | 0.84 | POLB (0.45) | NOS2 | |
| SCHEMBL17251486 | 0.81 | NAMPT (0.50) | NAMPTNOS2 | |
| SCHEMBL18632887 | 0.81 | L3MBTL1 (0.49) | NAMPTNOS2 | |
| SCHEMBL17293023 | 0.79 | NAMPT (0.51) | NAMPTNOS2 | |
| SCHEMBL20379406 | 0.77 | RECQL (0.49) | NAMPTNOS2 | |
| SCHEMBL9645727 | 0.75 | NAMPT (0.46) | NAMPTNOS2 | |
| SCHEMBL20671969 | 0.74 | NAMPT (0.52) | NAMPTHDAC6 | |
| SCHEMBL19318512 | 0.74 | HDAC6 (0.50) | NAMPTHDAC6CA1CA2CA7 | |
| SCHEMBL20233520 | 0.74 | HDAC6 (0.50) | HDAC6CA1CA2CA7CA14 | |
| SCHEMBL26077315 | 0.73 | NAMPT (0.45) | NAMPTNOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10173980-B2 | Mixed disulfide conjugates of thienopyridine compounds and uses thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2019-01-08 | — | — | US | disclosed |
| US-20180155289-A1 | MIXED DISULFIDE CONJUGATES OF THIENOPYRIDINE COMPOUNDS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2018-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10173980-B2 | Mixed disulfide conjugates of thienopyridine compounds and uses thereof | TST, TXN, TXNRD2 | NAMPT 710/4885HDAC6 281/4885CA1 3057/4885 |
| US-20180155289-A1 | MIXED DISULFIDE CONJUGATES OF THIENOPYRIDINE COMPOUNDS AND USES THEREOF | TST, TXN, TXNRD2 | NAMPT 710/4885HDAC6 281/4885CA1 3057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.