Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ACP1 | P24666 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | JUN | P05412 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26639301 | 0.89 | MAPT (0.54) | MAPTGPR35P2RX1LMNAACP1 | |
| SCHEMBL26623546 | 0.88 | MAPT (0.54) | MAPTGPR35P2RX1LMNAACP1 | |
| SCHEMBL5572981 | 0.84 | MAPT (0.61) | MAPTGPR35P2RX1LMNAACP1 | |
| SCHEMBL23060422 | 0.82 | MAPT (0.64) | MAPTP2RX1LMNAALDH1A1 | |
| SCHEMBL26626317 | 0.81 | EPHX2 (0.66) | LMNAALDH1A1 | |
| SCHEMBL23148069 | 0.81 | MAPT (0.62) | MAPTGPR35P2RX1LMNAACP1 | |
| SCHEMBL7692960 | 0.79 | GPR35 (0.74) | MAPTGPR35P2RX1LMNAACP1 | |
| SCHEMBL2681462 | 0.79 | MAPT (0.78) | MAPTGPR35P2RX1LMNAACP1 | |
| SCHEMBL26624050 | 0.78 | EGFR (0.40) | P2RX1P2RX4P2RX7CA1CA2 | |
| SCHEMBL11788448 | 0.78 | MAPT (0.63) | MAPTGPR35P2RX1LMNAACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230337677-A1 | ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2023-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230337677-A1 | ARYL AND PYRIDYL AMIDE PESTICIDES AND COMPOSITIONS THEREOF | DDT, ACHE, AHR | MAPT 1631/4885GPR35 1183/4885P2RX1 565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.