Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HPD | P32754 | 2/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | TYK2 | P29597 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | GNRHR | P30968 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31282399 | 1.00 | DDB1 (0.38) | DDB1CRBNHDAC1DRD2SLC6A4 | |
| SCHEMBL29172794 | 1.00 | DDB1 (0.38) | DDB1CRBNHDAC1DRD2SLC6A4 | |
| SCHEMBL26634973 | 0.99 | DDB1 (0.39) | DDB1CRBNHDAC1DRD2SLC6A4 | |
| SCHEMBL30225575 | 0.90 | HDAC1 (0.40) | DDB1CRBNHDAC1DRD2SLC6A4 | |
| SCHEMBL29991433 | 0.88 | DDB1 (0.39) | DDB1CRBNHDAC1DRD2SLC6A4 | |
| SCHEMBL31282297 | 0.86 | NMT1 (0.39) | DDB1CRBNHDAC1DRD2SLC6A4 | |
| SCHEMBL30225594 | 0.85 | NMT1 (0.39) | DDB1CRBNHDAC1DRD2SLC6A4 | |
| SCHEMBL30317066 | 0.84 | DRD2 (0.35) | DDB1CRBNHDAC1DRD2SLC6A4 | |
| SCHEMBL30317114 | 0.82 | DRD2 (0.40) | DDB1CRBNHDAC1DRD2SLC6A4 | |
| SCHEMBL30225615 | 0.82 | KHK (0.40) | DDB1CRBNHDAC1DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215906-A1 | KRAS G12D PROTEOLYSIS TARGETING CHIMERAS | HANGZHOU JIJING PHARMACEUTICALTECHNOLOGY LIMITED (CN) | 2023-11-09 | — | — | WO | disclosed |