Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 9/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | KHK | P50053 | 1/20 | 0.34 |
| ▸ | HPD | P32754 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30225615 | 0.93 | KHK (0.40) | DDB1CRBNDRD2SLC6A4HDAC1 | |
| SCHEMBL26634973 | 0.87 | DDB1 (0.39) | DDB1CRBNDRD2SLC6A4HDAC1 | |
| SCHEMBL30733897 | 0.87 | DDB1 (0.40) | DDB1CRBNDRD2SLC6A4HDAC1 | |
| SCHEMBL26635076 | 0.86 | DDB1 (0.38) | DDB1CRBNDRD2SLC6A4HDAC1 | |
| SCHEMBL29172794 | 0.86 | DDB1 (0.38) | DDB1CRBNDRD2SLC6A4HDAC1 | |
| SCHEMBL30225575 | 0.86 | HDAC1 (0.40) | DDB1CRBNDRD2SLC6A4HDAC1 | |
| SCHEMBL31282399 | 0.86 | DDB1 (0.38) | DDB1CRBNDRD2SLC6A4HDAC1 | |
| SCHEMBL29991433 | 0.86 | DDB1 (0.39) | DDB1CRBNDRD2SLC6A4HDAC1 | |
| SCHEMBL30225594 | 0.85 | NMT1 (0.39) | NMT1DDB1CRBNDRD2SLC6A4 | |
| SCHEMBL31282427 | 0.85 | DRD2 (0.41) | DDB1CRBNDRD2SLC6A4HPD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4731309-A1 | KRAS PROTEOLYSIS TARGETING CHIMERAS | Paq Therapeutics Inc. (US) | 2026-04-29 | — | — | EP | disclosed |
| WO-2024263586-A1 | KRAS PROTEOLYSIS TARGETING CHIMERAS | PAQ Therapeutics Inc. (US) | 2024-12-26 | — | — | WO | disclosed |