Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 2/20 | 0.41 |
| ▸ | VHL | P40337 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | USP8 | P40818 | 2/20 | 0.37 |
| ▸ | USP7 | Q93009 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30540161 | 1.00 | XDH (0.47) | XDHERN1VHLPDE10ACHEK1 | |
| SCHEMBL26635169 | 0.83 | XDH (0.46) | XDHERN1USP8USP7TDP1 | |
| SCHEMBL610902 | 0.80 | XDH (0.42) | XDHVHLPDE10ACHEK1TDP1 | |
| SCHEMBL30540164 | 0.80 | ALDH1A1 (0.51) | XDHERN1USP8USP7TDP1 | |
| SCHEMBL26635456 | 0.80 | ALDH1A1 (0.51) | XDHERN1USP8USP7TDP1 | |
| SCHEMBL30540273 | 0.78 | USP8 (0.44) | XDHERN1USP8USP7TDP1 | |
| SCHEMBL26635484 | 0.78 | USP8 (0.44) | XDHERN1USP8USP7TDP1 | |
| SCHEMBL26635345 | 0.78 | XDH (0.52) | XDHERN1USP8USP7TDP1 | |
| SCHEMBL30540283 | 0.77 | USP8 (0.43) | XDHERN1USP8USP7TDP1 | |
| SCHEMBL26635189 | 0.77 | USP8 (0.43) | XDHERN1USP8USP7TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023208151-A1 | USP INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION | 北京华森英诺生物科技有限公司 | 2023-11-02 | — | — | WO | disclosed |
| CN-116621778-A | USP inhibitor, preparation method and application thereof | 北京华森英诺生物科技有限公司 | 2023-08-22 | — | — | CN | disclosed |