Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP8 | P40818 | 2/20 | 0.44 |
| ▸ | USP7 | Q93009 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 2/20 | 0.42 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30540273 | 1.00 | USP8 (0.44) | USP8USP7XDHUSP47CNR2 | |
| SCHEMBL30540164 | 0.88 | ALDH1A1 (0.51) | USP8USP7XDHUSP47CNR2 | |
| SCHEMBL26635456 | 0.88 | ALDH1A1 (0.51) | USP8USP7XDHUSP47CNR2 | |
| SCHEMBL30540283 | 0.86 | USP8 (0.43) | USP8USP7XDHUSP47CNR2 | |
| SCHEMBL26635189 | 0.86 | USP8 (0.43) | USP8USP7XDHUSP47CNR2 | |
| SCHEMBL26635169 | 0.81 | XDH (0.46) | USP8USP7XDHUSP47ALDH1A1 | |
| SCHEMBL26635210 | 0.79 | XDH (0.47) | USP8USP7XDHCNR2ALDH1A1 | |
| SCHEMBL30540161 | 0.78 | XDH (0.47) | USP8USP7XDHUSP47CNR2 | |
| SCHEMBL26635296 | 0.78 | XDH (0.47) | USP8USP7XDHUSP47CNR2 | |
| SCHEMBL30540241 | 0.75 | XDH (0.51) | XDHCNR2ALDH1A1TDP1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023208151-A1 | USP INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION | 北京华森英诺生物科技有限公司 | 2023-11-02 | — | — | WO | disclosed |
| CN-116621778-A | USP inhibitor, preparation method and application thereof | 北京华森英诺生物科技有限公司 | 2023-08-22 | — | — | CN | disclosed |