Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 7/20 | 0.74 |
| ▸ | GAA | P10253 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 5/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.72 |
| ▸ | POLB | P06746 | 4/20 | 0.72 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.71 |
| ▸ | ESR1 | P03372 | 1/20 | 0.67 |
| ▸ | ESRRG | P62508 | 1/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.67 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
| ▸ | AHR | P35869 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28515978 | 0.89 | GAA (0.81) | GCGRGAAKDM4EMEN1KMT2A | |
| SCHEMBL2830968 | 0.86 | DNM1 (0.90) | GCGRGAADNM1ESR1ESRRG | |
| SCHEMBL2830971 | 0.86 | DNM1 (0.90) | GCGRGAADNM1ESR1ESRRG | |
| SCHEMBL13475421 | 0.86 | DNM1 (0.90) | GCGRGAADNM1ESR1ESRRG | |
| SCHEMBL2663821 | 0.85 | GCGR (1.00) | GCGRGAAKDM4EMEN1KMT2A | |
| SCHEMBL28521274 | 0.84 | GAA (0.77) | GCGRGAAKDM4EMEN1KMT2A | |
| SCHEMBL28521660 | 0.84 | GCGR (0.78) | GCGRGAAKDM4EMEN1KMT2A | |
| SCHEMBL11157751 | 0.84 | GAA (1.00) | GCGRGAAKDM4EMEN1KMT2A | |
| SCHEMBL28510648 | 0.84 | GAA (0.80) | GCGRGAAKDM4EMEN1KMT2A | |
| SCHEMBL2542993 | 0.83 | GAA (0.80) | GCGRGAAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |