SCHEMBL26651233

SCHEMBL26651233

CC(C)(C)C(=O)OCOP(=O)(OC[C@H]1O[C@@](C)(c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O)Oc1cccc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ POLRMT O00411 1/20 0.33
▸ BTN3A1 O00481 1/20 0.33
▸ RNASEL Q05823 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26651178 0.90 POLRMT (0.33) POLRMTRNASEL
SCHEMBL26637255 0.90 TMPRSS2 (0.41) POLRMTBTN3A1RNASEL
SCHEMBL24790439 0.90 RNASEL (0.35) POLRMTRNASEL
SCHEMBL24149793 0.82 POLRMT (0.32) POLRMT
SCHEMBL24917203 0.81 POLRMT (0.32) POLRMTRNASEL
SCHEMBL25607768 0.81 POLRMT (0.34) POLRMT
SCHEMBL25012573 0.81 POLRMT (0.32) POLRMT
SCHEMBL31684109 0.80 TMPRSS2 (0.40) POLRMT
SCHEMBL24916851 0.79 RNASEL (0.35) POLRMTRNASEL
SCHEMBL26637240 0.79 TMPRSS2 (0.43) POLRMTRNASEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230338409-A1 NUCLEOSIDE DRUGS FOR THE TREATMENT OR PREVENTION OF CORONAVIRUS INFECTION AND THEIR USES MIRACURE BIOTECHNOLOGY LTD (CN) 2023-10-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230338409-A1 NUCLEOSIDE DRUGS FOR THE TREATMENT OR PREVENTION OF CORONAVIRUS INFECTION AND THEIR USES PNP, MTAP, TYMP POLRMT 210/4885BTN3A1 4775/4885RNASEL 57/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback