Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 2/20 | 0.43 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26640069 | 1.00 | SIGMAR1 (0.49) | SIGMAR1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL27605968 | 0.85 | CYP2C19 (0.55) | KMT2AALDH1A1MEN1POLBLMNA | |
| SCHEMBL4849306 | 0.82 | SIGMAR1 (0.61) | SIGMAR1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL4855673 | 0.82 | SIGMAR1 (0.61) | SIGMAR1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL2852187 | 0.82 | SIGMAR1 (0.61) | SIGMAR1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL30642175 | 0.81 | CA12 (0.46) | SIGMAR1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL20640637 | 0.80 | TRPA1 (0.55) | SIGMAR1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL26640103 | 0.80 | SIGMAR1 (0.42) | SIGMAR1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL26640094 | 0.80 | SIGMAR1 (0.42) | SIGMAR1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL4846816 | 0.79 | ADAMTS4 (0.49) | SIGMAR1KMT2AALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220715-A1 | OXOINDOLINYL AMIDE DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2023-11-16 | — | — | WO | disclosed |