Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR1E | P28566 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4742791 | 1.00 | SLC6A2 (0.50) | SLC6A2TAAR1SLC6A4SLC6A3ADRB1 | |
| SCHEMBL5914402 | 1.00 | SLC6A2 (0.50) | SLC6A2TAAR1SLC6A4SLC6A3ADRB1 | |
| Hydrochloric Acid SCHEMBL724080 | 0.98 | SLC6A2 (0.49) | SLC6A2TAAR1SLC6A4SLC6A3ADRB1 | |
| Bromide SCHEMBL6052803 | 0.98 | SLC6A2 (0.49) | SLC6A2TAAR1SLC6A4SLC6A3ADRB1 | |
| Iodide SCHEMBL6052802 | 0.98 | SLC6A2 (0.49) | SLC6A2TAAR1SLC6A4SLC6A3ADRB1 | |
| SCHEMBL2857779 | 0.84 | SLC6A2 (0.61) | SLC6A2TAAR1SLC6A4SLC6A3ADRB1 | |
| SCHEMBL19971988 | 0.83 | CYP2D6 (0.47) | SLC6A2TAAR1SLC6A4SLC6A3HSPA5 | |
| SCHEMBL632694 | 0.83 | GABRA1 (0.55) | SLC6A2TAAR1SLC6A4SLC6A3MAOA | |
| SCHEMBL108067 | 0.82 | GABRA1 (0.64) | TAAR1HSPA5 | |
| SCHEMBL3071437 | 0.82 | HSPA5 (0.54) | SLC6A2TAAR1SLC6A4SLC6A3HSPA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3870170-B1 | TREATMENT OF PRESBYOPIA AND MYDRIASIS WITH PHENTOLAMINE | OPUS GENETICS INC (US) | 2026-02-25 | — | — | EP | claimed |
| EP-3413872-B1 | NON-INVASIVE OCULAR DRUG DELIVERY INSERT TECHNOLOGY | UNIV DE COIMBRA (PT) | 2024-10-02 | — | — | EP | claimed |
| EP-2991621-B1 | TWO-LAYER OCULAR IMPLANT | RETINA FOUND OF THE SOUTHWEST (US) | 2020-12-09 | — | — | EP | claimed |
| EP-2884962-B1 | PREPARATION OF DESICCATED LIPOSOMES FOR USE IN COMPRESSIBLE DELIVERY SYSTEMS | SMARTEK INT LLC (US) | 2019-05-01 | — | — | EP | claimed |
| US-9757376-B2 | Pharmaceutical compositions | GM PHARMACEUTICALS, INC. (US) | 2017-09-12 | — | — | US | claimed |
| CN-104277043-B | One-dimensional organic semiconductor nanotube and its preparation method and application | INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2017-01-04 | — | — | CN | claimed |
| EP-2493459-B1 | OCULAR DRUG DELIVERY DEVICES | ATON PHARMA INC (US) | 2016-08-24 | — | — | EP | claimed |
| EP-2991621-A2 | TWO-LAYER OCULAR IMPLANT | Odin Biotech (US) | 2016-03-09 | — | — | EP | claimed |
| EP-1825851-B1 | Combination therapy for effecting weight loss and treating obesity | VIVUS INC (US) | 2015-07-22 | — | — | EP | claimed |
| EP-2305227-B1 | Combination therapy for the treatment of diabetes associated with obesity | VIVUS INC (US) | 2015-05-06 | — | — | EP | claimed |
| EP-2352459-A1 | MACROCYCLIC LACTONE COMPOUNDS AND METHODS FOR THEIR USE | Elixir Medical Corporation (US) | 2011-08-10 | — | — | EP | claimed |
| EP-1671624-B1 | Delivery device for a controlled drug release of an active agent into the posterior section of the eye | SURMODICS INC (US) | 2010-08-11 | — | — | EP | claimed |
| WO-2010040064-A1 | MACROCYCLIC LACTONE COMPOUNDS AND METHODS FOR THEIR USE | ELIXIR MEDICAL CORPORATION (US) | 2010-04-08 | — | — | WO | claimed |
| EP-1276462-B1 | SUSTAINED RELEASE DRUG DELIVERY DEVICES, METHODS OF USE, AND METHODS OF MANUFACTURING THEREOF | PSIVIDA INC (US) | 2008-09-24 | — | — | EP | claimed |
| EP-1187603-B1 | COMBINATION THERAPY FOR EFFECTING WEIGHT LOSS AND TREATING OBESITY | VIVUS INC (US) | 2007-08-08 | — | — | EP | claimed |
| CN-1703199-A | Aggregate with enhanced deformability comprising at least three amphiphiles for improved transport through a semi-permeable barrier and use of non-invasive drugs in vivo, in particular through the skin | IDEA AG (DE) | 2005-11-30 | — | — | CN | claimed |
| US-6495154-B1 | ADMINISTERING ANTIDEPRESSANTS, ADRENERGIC STIMULANTS, SEROTONIN AGONISTS AND ANTAGONISTS AS THERAPEUTIC AGENTS FOR SEXUAL DISORDERS | VIVUS INC. | 2002-12-17 | — | — | US | claimed |
| EP-0126684-B1 | DRUG DELIVERY SYSTEM UTILIZING THERMOSETTING GELS | MERCK & CO. INC. (US) | 1991-08-28 | — | — | EP | claimed |
| EP-0046270-B1 | NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | INTERx RESEARCH CORPORATION (US) | 1986-05-21 | — | — | EP | claimed |
| EP-0152379-A2 | Process for preparing pharmaceutical compositions containing unilamellar liposomes | CIBA-GEIGY AG (CH) | 1985-08-21 | — | — | EP | claimed |