Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26643160 | 0.87 | KDM4E (0.37) | HPGDKDM4ENPC1RAB9AEGLN1 | |
| SCHEMBL26643225 | 0.83 | EGLN1 (0.38) | NOTUMHSD17B10HPGDKDM4ENPC1 | |
| SCHEMBL26769898 | 0.79 | NOS3 (0.37) | ELANEHPGDKDM4ESMN1; SMN2MAPT | |
| SCHEMBL15351384 | 0.77 | EGLN1 (0.43) | ELANEHSD17B10TP53EGLN1POLB | |
| SCHEMBL26643068 | 0.77 | LMNA (0.46) | HCRTR1KDM4ELMNAEGLN1MAPT | |
| SCHEMBL1672011 | 0.75 | HCRTR1 (0.45) | HCRTR1KDM4EMYCGABRPGABRD | |
| SCHEMBL26643032 | 0.72 | KDM4E (0.41) | NOTUMHCRTR1KDM4ENPC1RAB9A | |
| SCHEMBL1671789 | 0.72 | HCRTR1 (0.49) | NOTUMHCRTR1KDM4E | |
| SCHEMBL15350037 | 0.71 | ELANE (0.37) | ELANEHSD17B10HPGDLMNASMN1; SMN2 | |
| SCHEMBL31430855 | 0.71 | KDR (0.47) | NOTUMHSD17B10HPGDKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023218023-A1 | THIAZOLOARYL-METHYL SUBSTITUTED CYCLIC HYDRAZINE-N-CARBOXAMIDE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-11-16 | — | — | WO | disclosed |