Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26643225 | 0.87 | EGLN1 (0.38) | KDM4EMAPTMAPK1NPSR1L3MBTL1 | |
| SCHEMBL26643108 | 0.87 | NOTUM (0.37) | KDM4EMAPTL3MBTL1HPGDHTT | |
| SCHEMBL26643068 | 0.80 | LMNA (0.46) | KDM4EMAPTALDH1A1GAAPKM | |
| SCHEMBL17725519 | 0.79 | MYC (0.57) | KDM4EMAPTNPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL1672011 | 0.79 | HCRTR1 (0.45) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL26643032 | 0.76 | KDM4E (0.41) | KDM4EMAPTL3MBTL1GABRPGABRD | |
| SCHEMBL1671789 | 0.76 | HCRTR1 (0.49) | KDM4EALDH1A1GAAPKM | |
| SCHEMBL16277507 | 0.75 | CSNK2A1 (0.46) | KDM4EMAPTMAPK1NPSR1L3MBTL1 | |
| SCHEMBL30756500 | 0.73 | TDO2 (0.39) | KDM4EMAPTMAPK1NPSR1L3MBTL1 | |
| SCHEMBL612856 | 0.70 | KDM4E (0.48) | KDM4EHPGDGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023218023-A1 | THIAZOLOARYL-METHYL SUBSTITUTED CYCLIC HYDRAZINE-N-CARBOXAMIDE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-11-16 | — | — | WO | disclosed |