Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2664435 | 0.81 | GCGR (0.54) | GCGRMAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL2664404 | 0.76 | GCGR (0.82) | GCGR | |
| SCHEMBL2649228 | 0.74 | PTGDR2 (0.66) | MAPTL3MBTL1SMN1; SMN2TDP1PTGDR2 | |
| SCHEMBL2663792 | 0.73 | GCGR (0.50) | GCGRMAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL2649446 | 0.71 | KDM4E (0.61) | MAPTLMNANPC1SMN1; SMN2PTGDR2 | |
| SCHEMBL24133288 | 0.69 | USP2 (0.54) | MAPTLMNAMAPK1CASP3NPC1 | |
| SCHEMBL5881979 | 0.69 | PTGDR2 (0.59) | MAPTL3MBTL1RAB9ATDP1PTGDR2 | |
| SCHEMBL239362 | 0.68 | L3MBTL1 (0.50) | MAPTROCK2TNKSPARP1ROCK1 | |
| SCHEMBL16563628 | 0.68 | MMP2 (0.51) | MAPTNPC1RAB9ASMN1; SMN2TRPV1 | |
| SCHEMBL10260277 | 0.68 | ROCK2 (0.73) | MAPTROCK2TNKSPARP1ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |