SCHEMBL266444

SCHEMBL266444

COc1cc(C)nc2ccccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.64
HPGD P15428 2/20 0.64
SMN1; SMN2 Q16637 2/20 0.64
CYP1A2 P05177 1/20 0.60
ALOX15 P16050 1/20 0.60
HTT P42858 4/20 0.57
MAPT P10636 2/20 0.57
KDM4E B2RXH2 1/20 0.57
ALDH1A1 P00352 1/20 0.57
NCF1 P14598 2/20 0.56
GAA P10253 2/20 0.56
TSHR P16473 2/20 0.56
TP53 P04637 1/20 0.56
NQO2 P16083 1/20 0.52
POLB P06746 1/20 0.52
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
SLC2A1 P11166 1/20 0.51
NPC1 O15118 1/20 0.49
IGF1R P08069 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29877118 1.00 LMNA (0.64) LMNAHPGDSMN1; SMN2CYP1A2ALOX15
SCHEMBL25490903 0.83 NCF1 (0.59) LMNAHPGDSMN1; SMN2CYP1A2HTT
SCHEMBL3975907 0.83 CYP1A2 (0.58) LMNAHPGDSMN1; SMN2CYP1A2HTT
SCHEMBL7532440 0.81 CYP1A2 (0.56) LMNAHPGDSMN1; SMN2CYP1A2HTT
SCHEMBL30065410 0.81 HPGD (0.64) LMNAHPGDSMN1; SMN2ALOX15HTT
SCHEMBL396614 0.81 HPGD (0.64) LMNAHPGDSMN1; SMN2ALOX15HTT
SCHEMBL28010962 0.81 LMNA (0.64) LMNAHPGDSMN1; SMN2CYP1A2ALOX15
SCHEMBL423902 0.80 CYP1A2 (0.55) SMN1; SMN2CYP1A2NCF1GAATP53
SCHEMBL12283481 0.80 NCF1 (0.56) LMNASMN1; SMN2CYP1A2HTTNCF1
SCHEMBL9724306 0.79 KDM4E (0.59) LMNAHPGDSMN1; SMN2CYP1A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2119717-B1 8-[3-amino-piperidin-1-yl]-xanthins, their production and utilisation as DPP IV inhibitors BOEHRINGER INGELHEIM INT (DE) 2018-01-17 EP claimed
US-8697868-B2 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2014-04-15 US claimed
US-20090137801-A1 8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-05-28 US claimed
EP-1758905-B1 8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINE, THE PRODUCTION THEREOF AND THE USE IN THE FORM OF A DDP-IV INHIBITOR BOEHRINGER INGELHEIM INT (DE) 2009-04-29 EP claimed
US-20050234108-A1 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-10-20 US claimed
EP-0065192-B1 GROWTH-PROMOTING FODDER OR DRINKING LIQUID BASF Aktiengesellschaft (DE) 1984-02-01 EP claimed
CN-119285646-B Benzofuran acridine photoelectric material and preparation method and application thereof 烟台九目化学股份有限公司 2025-05-27 CN disclosed
CN-119285646-A Benzofuran acridine photoelectric material and preparation method and application thereof 烟台九目化学股份有限公司 2025-01-10 CN disclosed
US-20240218135-A1 PROTECTIVE FILM AND LAMINATE FUJIFILM CORPORATION (JP) 2024-07-04 US disclosed
US-20240118611-A1 TRANSFER FILM AND PHOTOSENSITIVE COMPOSITION FUJIFILM CORPORATION (JP) 2024-04-11 US disclosed
CN-117751328-A Protective film and laminate 富士胶片株式会社 2024-03-22 CN disclosed
CN-116982002-A Transfer film and photosensitive composition 富士胶片株式会社 2023-10-31 CN disclosed
CN-116888534-A Transfer film, pattern forming method, circuit wiring manufacturing method, and touch panel manufacturing method 富士胶片株式会社 2023-10-13 CN disclosed
US-4510146-A SUBSTITUTED QUINOLINE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1985-04-09 US disclosed
EP-0124752-A1 Mixtures of substances with growth and output accelerating effect as well as feed and watering liquids which contain low amounts of these mixtures BASF Aktiengesellschaft (DE) 1984-11-14 EP disclosed
EP-0065192-B1 GROWTH-PROMOTING FODDER OR DRINKING LIQUID BASF Aktiengesellschaft (DE) 1984-02-01 EP disclosed
EP-0065192-A1 Growth-promoting fodder or drinking liquid BASF Aktiengesellschaft (DE) 1982-11-24 EP disclosed
EP-0014929-B1 DIAGNOSTIC MEANS, PROCESS FOR ITS PREPARATION AND ITS USE IN DETERMINING LEUCOCYTES IN BODY FLUIDS Roche Diagnostics GmbH (DE) 1982-01-06 EP disclosed
US-4299917-A IMPREGNATION OF AN ABSORBENT CARRIER WITH A SULPHONPHTHALEIN ESTER AND AN ACTIVATOR BOEHRINGER MANNEHEIM GMBH (DE) 1981-11-10 US disclosed
EP-0014929-A1 Diagnostic means, process for its preparation and its use in determining leucocytes in body fluids Roche Diagnostics GmbH (DE) 1980-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137801-A1 8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS DPP8, DPP4, DPP7 LMNA 2911/4885HPGD 2402/4885SMN1; SMN2 2069/4885
US-20050234108-A1 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions DPP8, DPP4, DPP7 LMNA 1878/4885HPGD 2630/4885SMN1; SMN2 1725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.