Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | KRAS | P01116 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622433 | 1.00 | JAK3 (0.31) | JAK3KRASBTKSIGMAR1 | |
| SCHEMBL26645769 | 0.86 | EGFR (0.33) | BTKSIGMAR1 | |
| SCHEMBL30622334 | 0.86 | EGFR (0.33) | BTKSIGMAR1 | |
| SCHEMBL26645478 | 0.85 | GHSR (0.33) | SIGMAR1 | |
| SCHEMBL26645784 | 0.84 | MAPK11 (0.39) | JAK3BTK | |
| SCHEMBL26644893 | 0.84 | MAPK11 (0.39) | JAK3BTK | |
| SCHEMBL30622431 | 0.81 | GRM5 (0.36) | JAK3 | |
| SCHEMBL30622350 | 0.81 | GRM5 (0.36) | JAK3 | |
| SCHEMBL26645013 | 0.81 | GRM5 (0.36) | JAK3 | |
| SCHEMBL26645803 | 0.81 | GRM5 (0.36) | JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | claimed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |