Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 5/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 3/20 | 0.35 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30623073 | 1.00 | NR1H2 (0.41) | NR1H2NR1H3P2RY14GRM5SCN9A | |
| SCHEMBL30622961 | 0.90 | GRM5 (0.46) | GRM5SETD7PDK1PDK2TACR1 | |
| SCHEMBL30622799 | 0.90 | GRM5 (0.46) | GRM5SETD7PDK1PDK2TACR1 | |
| SCHEMBL30622912 | 0.88 | CACNB4 (0.39) | GRM5SETD7 | |
| SCHEMBL30622811 | 0.88 | CACNB4 (0.39) | GRM5SETD7 | |
| SCHEMBL26645036 | 0.86 | GRM5 (0.39) | GRM5PDK1PDK2 | |
| SCHEMBL26645490 | 0.86 | GRM5 (0.39) | GRM5PDK1PDK2 | |
| SCHEMBL26645099 | 0.80 | GRM5 (0.48) | NR1H2P2RY14GRM5MAPTGPR119 | |
| SCHEMBL30622988 | 0.79 | NR1H2 (0.39) | NR1H2NR1H3MAPTGPR119ENPP2 | |
| SCHEMBL30622801 | 0.79 | NR1H2 (0.39) | NR1H2NR1H3MAPTGPR119ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |