Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 2/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645317 | 0.85 | CSNK1D (0.38) | CSNK1DCSNK1EGPR119CKS1BSKP1 | |
| SCHEMBL30622970 | 0.85 | CSNK1D (0.38) | CSNK1DCSNK1EGPR119CKS1BSKP1 | |
| SCHEMBL26645466 | 0.85 | CSNK1D (0.49) | CSNK1DCSNK1EGPR119USP30MAPK1 | |
| SCHEMBL26645146 | 0.85 | CSNK1D (0.39) | CSNK1DCSNK1EUSP30NR1H2POLB | |
| SCHEMBL17129177 | 0.84 | CSNK1D (0.51) | CSNK1DCSNK1EGPR119USP30MAPK1 | |
| SCHEMBL26645108 | 0.84 | GPR119 (0.43) | CSNK1DCSNK1EGPR119MAPK1NR1H2 | |
| SCHEMBL26645250 | 0.83 | CSNK1D (0.48) | CSNK1DCSNK1EGPR119USP30MAPK1 | |
| SCHEMBL26645074 | 0.82 | CSNK1E (0.42) | CSNK1DCSNK1EMAPK1ALDH1A1 | |
| SCHEMBL26645019 | 0.82 | CSNK1D (0.47) | CSNK1DCSNK1EGPR119POLBCKS1B | |
| SCHEMBL26645681 | 0.82 | CSNK1E (0.48) | CSNK1DCSNK1EGPR119CKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |