Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 6/20 | 0.42 |
| ▸ | CDK9 | P50750 | 6/20 | 0.42 |
| ▸ | GALR2 | O43603 | 1/20 | 0.42 |
| ▸ | GALR1 | P47211 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | JAK1 | P23458 | 5/20 | 0.38 |
| ▸ | JAK2 | O60674 | 3/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622881 | 1.00 | CCNT1 (0.42) | CCNT1CDK9GALR2GALR1ROCK2 | |
| SCHEMBL26644930 | 0.89 | JAK3 (0.40) | ROCK2CYP3A4JAK3GSK3AGSK3B | |
| SCHEMBL30622359 | 0.89 | JAK3 (0.40) | ROCK2CYP3A4JAK3GSK3AGSK3B | |
| SCHEMBL30623060 | 0.87 | CCNT1 (0.43) | CCNT1CDK9GALR2GALR1BTK | |
| SCHEMBL26645701 | 0.86 | JAK1 (0.43) | CDK9JAK1JAK2JAK3PTK2 | |
| SCHEMBL30623059 | 0.86 | JAK1 (0.43) | CDK9JAK1JAK2JAK3PTK2 | |
| SCHEMBL26645714 | 0.84 | MKNK1 (0.48) | CCNT1CDK9CYP3A4JAK1JAK2 | |
| SCHEMBL26645791 | 0.82 | GALR2 (0.46) | CCNT1CDK9GALR2GALR1JAK1 | |
| SCHEMBL30623109 | 0.82 | GALR2 (0.46) | CCNT1CDK9GALR2GALR1JAK1 | |
| SCHEMBL30623070 | 0.81 | MKNK1 (0.45) | CCNT1CDK9CYP3A4JAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |