Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 6/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 3/20 | 0.36 |
| ▸ | CDK9 | P50750 | 4/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.35 |
| ▸ | CCNK | O75909 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCND3 | P30281 | 1/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30623070 | 0.96 | MKNK1 (0.45) | MKNK1USP30CYP3A4CYP3A5GPR119 | |
| SCHEMBL26644962 | 0.88 | JAK3 (0.43) | MKNK1BTK | |
| SCHEMBL30622362 | 0.88 | JAK3 (0.43) | MKNK1BTK | |
| SCHEMBL26645323 | 0.84 | CCNT1 (0.42) | MKNK1CYP3A4BTKJAK1CDK9 | |
| SCHEMBL30622881 | 0.84 | CCNT1 (0.42) | MKNK1CYP3A4BTKJAK1CDK9 | |
| SCHEMBL30623059 | 0.83 | JAK1 (0.43) | MKNK1GPR119BTKJAK1CDK9 | |
| SCHEMBL26645701 | 0.83 | JAK1 (0.43) | MKNK1GPR119BTKJAK1CDK9 | |
| SCHEMBL26645590 | 0.82 | CYP3A4 (0.41) | MKNK1USP30CYP3A4CYP3A5GPR119 | |
| SCHEMBL26645524 | 0.82 | MKNK1 (0.52) | MKNK1USP30CYP3A4CYP3A5GPR119 | |
| SCHEMBL30622787 | 0.81 | BTK (0.40) | MKNK1GPR119BTKJAK1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |