Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | BUB1 | O43683 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645539 | 0.79 | GPR119 (0.39) | NR1H2RORCHDAC1GPR119F2RL1 | |
| SCHEMBL26645305 | 0.78 | F2RL1 (0.42) | NR1H2RORCHDAC1MEN1KMT2A | |
| SCHEMBL26645063 | 0.76 | NR1H2 (0.38) | NR1H2USP2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL26645111 | 0.76 | NR1H2 (0.33) | NR1H2RORCBUB1 | |
| SCHEMBL30622794 | 0.74 | NR1H2 (0.35) | NR1H2RORCUSP2SMN1; SMN2GPR119 | |
| SCHEMBL26645573 | 0.74 | NR1H2 (0.44) | NR1H2RORCHDAC1GPR119ESR2 | |
| SCHEMBL30622818 | 0.66 | SETD7 (0.34) | NR1H2HDAC1GPR119MEN1KMT2A | |
| SCHEMBL26645349 | 0.66 | SETD7 (0.34) | NR1H2HDAC1GPR119MEN1KMT2A | |
| SCHEMBL30622784 | 0.66 | SETD7 (0.34) | NR1H2HDAC1GPR119MEN1KMT2A | |
| SCHEMBL16709107 | 0.65 | NR1H2 (0.35) | NR1H2GPR119JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |