Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.30 |
| ▸ | BUB1 | O43683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645264 | 0.81 | RORC (0.38) | NR1H2RORC | |
| SCHEMBL26645385 | 0.79 | GPR119 (0.35) | NR1H2RORCBUB1 | |
| SCHEMBL26645063 | 0.76 | NR1H2 (0.38) | NR1H2 | |
| SCHEMBL26645404 | 0.76 | NR1H2 (0.40) | NR1H2RORCBUB1 | |
| SCHEMBL26645024 | 0.74 | NR1H2 (0.36) | NR1H2RORCBUB1 | |
| SCHEMBL30622784 | 0.73 | SETD7 (0.34) | NR1H2 | |
| SCHEMBL30622818 | 0.73 | SETD7 (0.34) | NR1H2 | |
| SCHEMBL26645349 | 0.73 | SETD7 (0.34) | NR1H2 | |
| SCHEMBL16699444 | 0.67 | ADORA1 (0.32) | NR1H2 | |
| SCHEMBL30622794 | 0.67 | NR1H2 (0.35) | NR1H2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |