Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 4/20 | 0.54 |
| ▸ | GALR1 | P47211 | 3/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | F13A1 | P00488 | 2/20 | 0.39 |
| ▸ | TGM2 | P21980 | 2/20 | 0.39 |
| ▸ | TGM1 | P22735 | 2/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 2/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622856 | 1.00 | GALR2 (0.54) | GALR2GALR1NR1H2JAK2JAK3 | |
| SCHEMBL30623068 | 0.99 | GALR2 (0.53) | GALR2GALR1NR1H2JAK2JAK3 | |
| SCHEMBL26645091 | 0.99 | GALR2 (0.53) | GALR2GALR1NR1H2JAK2JAK3 | |
| SCHEMBL26645720 | 0.86 | NR1H2 (0.44) | GALR2GALR1NR1H2JAK2JAK3 | |
| SCHEMBL26645416 | 0.82 | MAPT (0.53) | NR1H2JAK2JAK3PTK2JAK1 | |
| SCHEMBL26645516 | 0.82 | NR1H2 (0.46) | NR1H2JAK2JAK3JAK1NAMPT | |
| SCHEMBL30622995 | 0.82 | CFTR (0.44) | GALR2GALR1NR1H2ALDH1A1STS | |
| SCHEMBL26645173 | 0.82 | MAPT (0.52) | NR1H2JAK2JAK3PTK2JAK1 | |
| SCHEMBL26645025 | 0.82 | CFTR (0.44) | GALR2GALR1NR1H2ALDH1A1STS | |
| SCHEMBL26645138 | 0.81 | GALR2 (0.48) | GALR2GALR1JAK2JAK3PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |