Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 14/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.40 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31004951 | 0.84 | SMARCA2 (0.45) | GRM5NR1H2MEN1KMT2ASMARCA2 | |
| SCHEMBL19549826 | 0.82 | CD274 (0.53) | GRM5NR1H2SMARCA2SMARCA4PBRM1 | |
| SCHEMBL26645030 | 0.81 | HTT (0.55) | GRM5NR1H2MEN1KMT2A | |
| SCHEMBL16682723 | 0.81 | GRM5 (0.67) | GRM5 | |
| SCHEMBL30622995 | 0.81 | CFTR (0.44) | GRM5NR1H2MEN1KMT2ACFTR | |
| SCHEMBL26645025 | 0.81 | CFTR (0.44) | GRM5NR1H2MEN1KMT2ACFTR | |
| SCHEMBL30622947 | 0.81 | CFTR (0.44) | GRM5NR1H2MEN1KMT2AMAPK1 | |
| SCHEMBL26645632 | 0.81 | CFTR (0.44) | GRM5NR1H2MEN1KMT2AMAPK1 | |
| SCHEMBL26645772 | 0.80 | GRM5 (0.51) | GRM5NR1H2MEN1KMT2A | |
| SCHEMBL16711314 | 0.79 | GRM5 (0.50) | GRM5NR1H2GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |