Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 2/20 | 0.45 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 9/20 | 0.41 |
| ▸ | F12 | P00748 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645545 | 0.84 | GRM5 (0.45) | SMARCA2SMARCA4PBRM1NR1H2GRM5 | |
| SCHEMBL31004926 | 0.80 | SMARCA2 (0.41) | SMARCA2SMARCA4PBRM1NR1H2F12 | |
| SCHEMBL19549826 | 0.79 | CD274 (0.53) | SMARCA2SMARCA4PBRM1NR1H2GRM5 | |
| SCHEMBL26645772 | 0.79 | GRM5 (0.51) | NR1H2GRM5HTTMEN1KMT2A | |
| SCHEMBL26645030 | 0.77 | HTT (0.55) | NR1H2GRM5HTTMEN1KMT2A | |
| SCHEMBL23389957 | 0.76 | GRM5 (0.67) | NR1H2GRM5 | |
| SCHEMBL29796602 | 0.76 | GRM5 (0.67) | NR1H2GRM5 | |
| SCHEMBL12307412 | 0.76 | NR1H2 (0.48) | SMARCA2SMARCA4PBRM1NR1H2GRM5 | |
| SCHEMBL18200199 | 0.76 | GRM5 (0.52) | NR1H2GRM5 | |
| SCHEMBL16711195 | 0.76 | GRM5 (0.50) | NR1H2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024174229-A1 | COVALENT BINDING COMPOUNDS AND COMPOSITIONS | ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO., LTD. (CN) | 2024-08-29 | — | — | WO | disclosed |