Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 7/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 7/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16711450 | 0.89 | CSNK1E (0.52) | CSNK1DCSNK1EMMP13 | |
| SCHEMBL26645223 | 0.86 | ALDH1A1 (0.48) | MAPTGPR119CSNK1EMMP13 | |
| SCHEMBL26645705 | 0.85 | CSNK1D (0.46) | MAPTGPR119CSNK1DCSNK1ECTSS | |
| SCHEMBL26645527 | 0.85 | CSNK1E (0.41) | CSNK1DCSNK1E | |
| SCHEMBL26645364 | 0.82 | CSNK1E (0.45) | GPR119CSNK1DCSNK1E | |
| SCHEMBL16711190 | 0.82 | CSNK1E (0.55) | CSNK1DCSNK1E | |
| SCHEMBL30622988 | 0.82 | NR1H2 (0.39) | MAPTGPR119CTSSENPP2 | |
| SCHEMBL30622801 | 0.82 | NR1H2 (0.39) | MAPTGPR119CTSSENPP2 | |
| SCHEMBL30623018 | 0.81 | CSNK1E (0.44) | GPR119CSNK1DCSNK1E | |
| SCHEMBL26645586 | 0.81 | CSNK1E (0.44) | GPR119CSNK1DCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |