Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 7/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 5/20 | 0.40 |
| ▸ | RORC | P51449 | 3/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26644843 | 0.85 | JAK3 (0.39) | CSNK1ECSNK1D | |
| SCHEMBL30622317 | 0.85 | JAK3 (0.39) | CSNK1ECSNK1D | |
| SCHEMBL26645508 | 0.84 | CDK9 (0.39) | CYP3A4CYP3A5MKNK1CSNK1ECSNK1D | |
| SCHEMBL30622918 | 0.84 | CDK9 (0.39) | CYP3A4CYP3A5MKNK1CSNK1ECSNK1D | |
| SCHEMBL26645714 | 0.82 | MKNK1 (0.48) | CYP3A4CYP3A5MKNK1CDK9USP30 | |
| SCHEMBL26645116 | 0.82 | CYP3A4 (0.45) | CYP3A4CYP3A5MKNK1CSNK1ECSNK1D | |
| SCHEMBL30622436 | 0.81 | JAK3 (0.42) | CSNK1ECSNK1D | |
| SCHEMBL26645860 | 0.81 | CSNK1D (0.41) | CSNK1ECSNK1DRORCCDK9CCNT1 | |
| SCHEMBL30622795 | 0.80 | CSNK1E (0.42) | CSNK1ECSNK1DCDK9CCNT1 | |
| SCHEMBL26645523 | 0.80 | CSNK1E (0.42) | CSNK1ECSNK1DCDK9CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |