Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 6/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.35 |
| ▸ | CCNK | O75909 | 1/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622918 | 1.00 | CDK9 (0.39) | CDK9CCNT1BTKGPR119JAK1 | |
| SCHEMBL30622787 | 0.91 | BTK (0.40) | CDK9CCNT1BTKGPR119JAK1 | |
| SCHEMBL26645177 | 0.91 | BTK (0.40) | CDK9CCNT1BTKGPR119JAK1 | |
| SCHEMBL26645007 | 0.85 | JAK1 (0.43) | JAK1CSNK1DCCNKCDK12MAPK1 | |
| SCHEMBL30623067 | 0.85 | JAK1 (0.43) | JAK1CSNK1DCCNKCDK12MAPK1 | |
| SCHEMBL26645590 | 0.84 | CYP3A4 (0.41) | CDK9CCNT1GPR119CSNK1DCSNK1E | |
| SCHEMBL26645523 | 0.80 | CSNK1E (0.42) | CDK9CCNT1BTKCSNK1DCSNK1E | |
| SCHEMBL30622795 | 0.80 | CSNK1E (0.42) | CDK9CCNT1BTKCSNK1DCSNK1E | |
| SCHEMBL26645108 | 0.79 | GPR119 (0.43) | GPR119CSNK1DCSNK1EMAPK1NR1H2 | |
| SCHEMBL30623060 | 0.78 | CCNT1 (0.43) | CDK9CCNT1BTKCSNK1DCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |