Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.37 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | BUB1 | O43683 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622869 | 1.00 | USP30 (0.39) | USP30GPR119SETD7MAP4K4KCNK3 | |
| SCHEMBL30622743 | 1.00 | USP30 (0.39) | USP30GPR119SETD7MAP4K4KCNK3 | |
| SCHEMBL26645666 | 0.85 | SMO (0.34) | — | |
| SCHEMBL26645383 | 0.85 | SMO (0.34) | — | |
| SCHEMBL26645595 | 0.85 | SMO (0.34) | — | |
| SCHEMBL30622927 | 0.83 | KCNK3 (0.41) | USP30GPR119SETD7KCNK3KCNK9 | |
| SCHEMBL30622908 | 0.83 | KCNK3 (0.41) | USP30GPR119SETD7KCNK3KCNK9 | |
| SCHEMBL30622868 | 0.82 | SRC (0.38) | USP30GPR119SETD7MMP13 | |
| SCHEMBL30622834 | 0.80 | MAPK8 (0.36) | USP30GPR119KCNK3KCNK9UCHL1 | |
| SCHEMBL26645301 | 0.80 | CSNK1D (0.44) | USP30GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |