Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645595 | 1.00 | SMO (0.34) | SMOGAANPC1GHSRTOP2A | |
| SCHEMBL26645383 | 1.00 | SMO (0.34) | SMOGAANPC1GHSRTOP2A | |
| SCHEMBL30622743 | 0.85 | USP30 (0.39) | — | |
| SCHEMBL30622869 | 0.85 | USP30 (0.39) | — | |
| SCHEMBL26645802 | 0.85 | USP30 (0.39) | — | |
| SCHEMBL26645621 | 0.81 | MAPK14 (0.40) | SMO | |
| SCHEMBL26645097 | 0.81 | MAPK14 (0.40) | SMO | |
| SCHEMBL26645239 | 0.79 | SRC (0.41) | SMOGAA | |
| SCHEMBL26645255 | 0.77 | SMO (0.34) | SMOGAANPC1GHSRTOP2A | |
| SCHEMBL26645369 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |