Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21502038 | 1.00 | TSHR (0.33) | TSHRADAM10ERBB2CHRNB2CHRNB4 | |
| SCHEMBL21150127 | 0.82 | TSHR (0.37) | TSHRADAM10ERBB2CHRNB2CHRNB4 | |
| SCHEMBL23634215 | 0.80 | CHRNB2 (0.35) | CHRNB2CHRNB4CHRNA3CHRNA4LMNA | |
| SCHEMBL17173156 | 0.80 | HSD11B1 (0.41) | — | |
| SCHEMBL17173155 | 0.80 | HSD11B1 (0.41) | — | |
| SCHEMBL12206734 | 0.80 | POLB (0.36) | TSHR | |
| SCHEMBL19037496 | 0.78 | DPP4 (0.39) | — | |
| SCHEMBL19037493 | 0.78 | DPP4 (0.39) | — | |
| SCHEMBL12206717 | 0.77 | TSHR (0.33) | TSHRLMNAHTTNPSR1 | |
| SCHEMBL12206718 | 0.77 | SLC6A2 (0.38) | TSHRADAM10ERBB2CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3784669-B1 | PTERIDINONE COMPOUNDS AND USES THEREOF | VERTEX PHARMA (US) | 2023-10-25 | — | — | EP | disclosed |